产前二维与三维超声骨骼成像技术诊断人体鱼序列综合征

发布时间：2018-07-30 08:22

【摘要】：目的评价产前二维和三维超声骨骼成像技术诊断人体鱼序列综合征。方法产前二维超声怀疑或提示人体鱼序列综合征10例,再行三维超声骨骼成像检查,与引产后三维螺旋CT、X线检查及病理进行对照。结果 9例为单胎,1例为联体双胎。10例胎儿均终止妊娠,染色体与生后病理提示5例男性,5例女性。二维超声提示10例均有羊水少、双肾膀胱缺如、单脐动脉及双下肢不同程度的融合;双足融合或单足8例,无足2例,脊柱异常10例,心脏畸形8例。三维超声骨骼成像提示脊柱侧弯9例,骶尾椎发育不良10例,半椎体3例,融合椎1例,开放性脊柱裂3例,肋骨异常5例,与引产后三维螺旋CT、X线及病理结果显示一致。结论二维超声能够很好怀疑或提示人体鱼序列综合征,而三维超声骨骼成像技术以无创、便捷地提供了酷似三维螺旋CT的骨骼成像,有利于更早地认识人体鱼序列综合征胎儿的骨骼异常,有助于产前超声诊断。
[Abstract]:Objective to evaluate prenatal two-dimensional and three-dimensional ultrasound bone imaging for the diagnosis of fish sequence syndrome. Methods Ten cases of fish sequence syndrome suspected or prompted by prenatal two-dimensional ultrasound were examined by three-dimensional ultrasound bone imaging and compared with three-dimensional spiral CT X-ray examination and pathology after induced labor. Results 9 cases were single twins 1 case was conjoined twins. 10 cases of fetuses terminated pregnancy. Chromosome and postnatal pathology showed 5 cases of male and 5 cases of female. Two-dimensional ultrasound showed that 10 cases had amniotic fluid oligohydramnios, both kidney and bladder were absent, one umbilical artery and lower extremity were fused to different degrees, 8 cases had bipedal fusion, 2 cases had no foot, 10 cases had spinal abnormality, and 8 cases had heart malformation. Three-dimensional ultrasound bone imaging revealed 9 cases of scoliosis, 10 cases of sacrocaudal dysplasia, 3 cases of hemivertebra, 1 case of fusion vertebra, 3 cases of open spina bifida and 5 cases of rib abnormality. Conclusion Two-dimensional ultrasound can well suspect or prompt fish sequence syndrome, and three-dimensional ultrasound bone imaging technology can provide three-dimensional spiral CT like bone imaging conveniently and noninvasively. It is helpful to recognize the skeletal abnormalities of human fetal fish sequence syndrome earlier and to help prenatal ultrasound diagnosis.
【作者单位】：三峡大学医学影像研究所宜昌市中心人民医院超声科;湖北省妇幼保健院超声科;武汉市儿童医院CT室;
【分类号】：R445.1;R714.5

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