脑卒中高危人群视网膜中央动脉血流动力学与亚临床脑梗死的相关性研究

发布时间：2018-08-09 07:31

【摘要】：目的:采用超声多普勒检测视网膜中央动脉(CRA)的血流动力学参数,并与亚临床脑梗死(SBI)做相关性分析,探讨其对SBI的预测作用。方法:149例脑卒中高危人群行MRI颅脑扫描,将其分为62例MRI有梗死灶的SBI组(观察组)和87例MRI无梗死灶的正常组(对照组)。应用彩色超声诊断仪检查CRA的血流频谱,测量CRA收缩期最大峰值血流速度(PSV)、舒张末期血流速度(EDV)、血流阻力指数(RI)。采用SAS统计软件做两样本的t检验。结果:观察组MRI脑梗死灶总数226个,主要分布于额叶及基底神经节,大小3~10mm。观察组CRA的PSV和EDV较对照组显著降低,RI显著增高。结论:脑卒中高危人群中SBI患者存在CRA血流动力学改变,高危人群中CRA血流动力学参数可以作为SBI的筛查指标。
[Abstract]:Objective: to detect the hemodynamic parameters of the central retinal artery (CRA) by ultrasonic Doppler, and to analyze the correlation with subclinical cerebral infarction (SBI), and to explore its predictive effect on SBI. Methods: 149 patients with high risk of stroke were divided into 62 cases of SBI (observation group) with MRI with infarct and 87 cases of MRI without infarction. Normal group (control group). The blood flow spectrum of CRA was examined by color ultrasonic diagnostic instrument. The maximum peak blood flow velocity (PSV), end diastolic velocity (EDV) and blood flow resistance index (RI) were measured for CRA. The t test of two samples was done by SAS software. Results: the total number of MRI cerebral infarction in the observation group was 226, mainly distributed in the frontal and basal ganglia, The PSV and EDV of CRA in the 3~10mm. observation group were significantly lower than those in the control group, and the RI was significantly higher. Conclusion: there were CRA hemodynamic changes in SBI patients at high risk of stroke, and the hemodynamic parameters of CRA in high-risk groups could be used as a screening index for SBI.
【作者单位】：湖北省中山医院超声影像科;湖北省中山医院MRI室;湖北省中山医院TCD室;
【基金】：湖北省卫生厅科研立项一般项目(JX5B38)
【分类号】：R445.1;R743.3

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