超声二维斑点追踪技术及实时三维超声心动图评价无症状饮酒者左心房功能的变化
发布时间：2018-08-17 11:28
【摘要】：目的:应用二维斑点追踪成像(2D-STE)技术及实时三维超声心动图(RT-3DE)评价无症状饮酒者随着饮酒时间因素的改变对左心房功能的影响。方法:选取30例在我院体检健康的不饮酒男性作为A组(对照组)。选取92例无临床症状的男性饮酒者,饮酒时间大于5年,日饮酒量白酒90~120g(即纯乙醇75~100ml)或啤酒2~3瓶(1000~1500ml)。根据饮酒时间的长短将其分为三组:B组:30名,饮酒时间5~9年(平均为7±2年);C组:31名,饮酒时间10~15年(平均为12±1年);D组:31名,饮酒时间大于15年(平均为18±2年)。均排除冠心病、高血压、糖尿病、心肌病、心律失常、心脏瓣膜病等心血管疾病及肝损害、肾损害等其他高危因素。1、对A、B、C、D四组行常规超声检查。常规测量参数包括:左室舒张末期内径(LVDd)、左室收缩末期内径(LVDs)、舒张末期室间隔厚度(IVSTd)、舒张末期左室后壁厚度(PWd)、左室射血分数(LVEF)以及短轴缩短率(FS);应用左心房(LA)容积曲线测量左心房最大容积(LAVmax)、最小容积(LAVmin)及左心房收缩前容积(LAVp),通过计算得到左心房被动射血分数(LAPEF)及左心房主动射血分数(LAAEF)。2、对A、B、C、D四组行2D-STE检查。2D-STE测量指标包括:心室收缩期左心房整体应变率(SRs),心室舒张早期左心房整体应变率(SRe),心室舒张晚期左心房整体应变率(SRa)。3、对A、B、C、D四组行RT-3DE检查。RT-3DE测量参数包括左心房最大容积(LAVmax)、最小容积(LAVmin)、左心房主动收缩前容积(LAVp)、左心房被动射血分数(LAPEF)、左心房主动射血分数(LAAEF)。结果:1、常规超声检查结果:B组所有指标与A组比较无统计学意义(均P0.05)。C组LAVmin、LAVmax、LAVp及LAAEF与A、B组比较明显增大(均P0.05),LAPEF明显减少(均P0.05)。D组LVDd、LVDs、IVSTd、PWd、LAVmin、LAVmax及LAVp与A、B、C组比较明显增大(均P0.05),LVEF、FS、LAPEF及LAAEF明显减少(均P0.05)。2、2D-STE检查结果:B组所有指标与A组比较无统计学意义(均P0.05)。C组SRa与A、B组比较明显增大(均P0.05),SRs及SRe明显减少(均P0.05)。D组与A、B、C组比较SRs、SRe及SRa明显减少(均P0.05)。3、RT-3DE检查结果:B组所有指标与A组比较无统计学意义(均P0.05)。C组LAVmin、LAVmax、LAVp、LAAEF与A、B组比较明显增大(均P0.05),LAPEF明显减少(均P0.05)。D组LAVmin、LAVmax及LAVp与A、B、C组比较明显增大(均P0.05),LAPEF、LAAEF明显减少(均P0.05)。结论:1、左房功能的损害会根据饮酒时间的改变而改变,2D-STE技术能够有效评价无症状饮酒者随着饮酒时间因素改变左心房功能的变化情况。2、RT-3DE可以有效评估左心房储存、通道、助力泵三大功能,能够反映无症状饮酒者随着饮酒时间因素改变左心房功能的变化情况,可被视为评估左心房容量和作用的精准、高效和可靠的衡量依据。
[Abstract]:Objective: To evaluate the effect of asymptomatic drinkers on left atrial function with the change of drinking time by two-dimensional speckle tracking imaging (2D-STE) and real-time three-dimensional echocardiography (RT-3DE). They were divided into three groups according to the drinking time: group B: 30, drinking for 5 to 9 years (average 7 2 years); group C: 31, drinking for 10 to 15 years (average 12 1 year); group D: 31, drinking for more than 15 years (average 18 2 years). Cardiovascular diseases such as coronary heart disease, hypertension, diabetes, cardiomyopathy, arrhythmia, heart valve disease, liver damage, kidney damage and other high-risk factors were excluded. Left atrial passive ejection fraction (LAPEF) and left atrial active ejection fraction (LAAEF) were calculated by measuring left atrial maximum volume (LAVmax), minimum volume (LAVmin) and left atrial pre-systolic volume (LAVp). 2. Four groups A, B, C, D were examined by 2D-STE. The two-dimensional-STE measurements included: left atrial global strain rate (SRs), early diastolic global strain rate (SRe), late diastolic global strain rate (SRa). Results: 1. Routine ultrasonography showed that there was no significant difference in all indexes between group B and group A (all P 0.05). In group C, LAVmin, LAVmax, LAVp and LAAEF were significantly increased (all P 0.05), and LAPEF was significantly decreased (all P 0.05). LVDd, LVDs, IVSTd, PWd, LAVmin, LAVmax, LAVp and A, B, C group were significantly increased (all P 0.05), LVEF, FS, LAPEF and LAAEF were significantly decreased (all P 0.05). 2, 2-D-STE results: All indicators in group B were not statistically significant compared with group A (all P 0.05). SRa and A in group C were significantly increased (all P 0.05), SRs and SRe were significantly decreased (all P 0.05). Compared with group A, B, C, SRs, SRe and SRa decreased significantly (all P 0.05). 3, RT-3DE results: All the indicators of group B and group A were not statistically significant (all P 0.05). Group C LAVmin, LAVmax, LAVp, LAAEF and group A, B were significantly increased (all P 0.05), LAPEF decreased significantly (all P 0.05). Group D LAVmin, LAVmax and LAVp were significantly increased compared with group A, B, C (all P 0.05). Conclusion: 1. The impairment of left atrial function can be changed according to the change of drinking time. 2. RT-3DE can effectively evaluate the changes of left atrial function in asymptomatic drinkers with the change of drinking time. Alcoholics'changes in left atrial function as a result of time consuming can be regarded as an accurate, efficient and reliable measure of left atrial volume and function.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R540.45
本文编号：2187490
[Abstract]:Objective: To evaluate the effect of asymptomatic drinkers on left atrial function with the change of drinking time by two-dimensional speckle tracking imaging (2D-STE) and real-time three-dimensional echocardiography (RT-3DE). They were divided into three groups according to the drinking time: group B: 30, drinking for 5 to 9 years (average 7 2 years); group C: 31, drinking for 10 to 15 years (average 12 1 year); group D: 31, drinking for more than 15 years (average 18 2 years). Cardiovascular diseases such as coronary heart disease, hypertension, diabetes, cardiomyopathy, arrhythmia, heart valve disease, liver damage, kidney damage and other high-risk factors were excluded. Left atrial passive ejection fraction (LAPEF) and left atrial active ejection fraction (LAAEF) were calculated by measuring left atrial maximum volume (LAVmax), minimum volume (LAVmin) and left atrial pre-systolic volume (LAVp). 2. Four groups A, B, C, D were examined by 2D-STE. The two-dimensional-STE measurements included: left atrial global strain rate (SRs), early diastolic global strain rate (SRe), late diastolic global strain rate (SRa). Results: 1. Routine ultrasonography showed that there was no significant difference in all indexes between group B and group A (all P 0.05). In group C, LAVmin, LAVmax, LAVp and LAAEF were significantly increased (all P 0.05), and LAPEF was significantly decreased (all P 0.05). LVDd, LVDs, IVSTd, PWd, LAVmin, LAVmax, LAVp and A, B, C group were significantly increased (all P 0.05), LVEF, FS, LAPEF and LAAEF were significantly decreased (all P 0.05). 2, 2-D-STE results: All indicators in group B were not statistically significant compared with group A (all P 0.05). SRa and A in group C were significantly increased (all P 0.05), SRs and SRe were significantly decreased (all P 0.05). Compared with group A, B, C, SRs, SRe and SRa decreased significantly (all P 0.05). 3, RT-3DE results: All the indicators of group B and group A were not statistically significant (all P 0.05). Group C LAVmin, LAVmax, LAVp, LAAEF and group A, B were significantly increased (all P 0.05), LAPEF decreased significantly (all P 0.05). Group D LAVmin, LAVmax and LAVp were significantly increased compared with group A, B, C (all P 0.05). Conclusion: 1. The impairment of left atrial function can be changed according to the change of drinking time. 2. RT-3DE can effectively evaluate the changes of left atrial function in asymptomatic drinkers with the change of drinking time. Alcoholics'changes in left atrial function as a result of time consuming can be regarded as an accurate, efficient and reliable measure of left atrial volume and function.
【学位授予单位】：大连医科大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R540.45
【参考文献】
相关期刊论文 前10条
1 黄红梅;刘艳午;曹礼庭;熊云涛;赵亚西;苟连平;吕湛;;三维斑点追踪成像评价冠心病患者左心室缺血心肌节段应变[J];中国医学影像技术;2015年08期
2 高磊;刘昕;郭淑芹;李春擎;;实时三维斑点追踪成像评价2型糖尿病血糖控制不良患者左心室整体收缩功能[J];中国医学影像学杂志;2015年06期
3 朱菲菲;刘表虎;李国杰;江峰;朱向明;;三维超声斑点追踪成像评价急性心肌梗死患者左室扭转运动的价值[J];临床超声医学杂志;2015年02期
4 单国鑫;礼广森;郭丽娟;徐瑞;;实时三平面超声心动图及全容积三维超声心动图评价酒精性心肌病患者左心房功能[J];中国医学影像技术;2014年02期
5 闫艳;李东野;王志荣;王晓萍;陈静;陈军红;;二维斑点追踪显像及实时三维成像技术评价风湿性心脏病二尖瓣狭窄患者左心房功能[J];现代医学;2013年11期
6 陈明;方少兵;刘衍斌;李桔莲;程起;周小英;相广财;;实时三维超声心动图左心房容积指数评价2型糖尿病患者左心房功能[J];中国医药导报;2013年19期
7 徐瑞;礼广森;单国鑫;郭丽娟;;定量组织速度成像评价酒精性心肌病患者左心房功能[J];中华临床医师杂志(电子版);2013年13期
8 张群英;龚兰;任伯绪;彭家清;邢天柱;秦鹏;曹乐;;定量组织速度成像评价透析对尿毒症患者左心房功能的影响[J];医学研究杂志;2013年04期
9 宋晓坤;任卫东;张光华;尹光宇;曲冉;;实时三维超声心动图评价原发性高血压病患者左心房容积和收缩功能的临床价值[J];临床超声医学杂志;2012年10期
10 李滨滨;吴红宁;曹怡;王燕;;应用定量组织速度成像技术评价高血压患者左心房机械功能[J];现代医学;2011年06期
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