不同应变率比值计算方法在甲状腺恶性肿瘤诊断中的应用
发布时间：2018-08-18 11:47
【摘要】：目的弹性成像技术存在敏感度差等不利因素,因此限制了该技术在甲状腺结节诊断中的应用,本研究以弹性应变率比值(SR)法为基础,针对不同大小的甲状腺结节采用不同的SR计算方法,以探讨不同SR计算方法在甲状腺结节良恶性鉴别中的应用价值。资料与方法回顾性分析行甲状腺弹性超声检查、超声引导下甲状腺细针穿刺的336例患者共340个结节,以细胞病理结合随访为标准,分析固定面积法和实际面积法在不同大小甲状腺结节良恶性鉴别中的差异。结果超声诊断340个结节中,小结节91例,大结节249例。病理诊断91例小结节中恶性36例,良性55例;249例大结节中恶性104例,良性145例。对于纵、横径均≤8 mm的小结节,实际面积法判断恶性肿瘤与病理的一致性更优(χ2=20.89,P0.01);对于纵径/横径8 mm的大结节,固定面积法更优(χ2=57.08,P0.01)。实际面积法诊断恶性结节的敏感度为57.10%,特异度为83.00%,符合率为72.30%(Kappa=0.413);固定面积法的诊断敏感度为73.60%,特异度为85.00%,符合率为80.30%(Kappa=0.590);根据结节大小选择性使用两种方法诊断的敏感度为85.00%,特异度为85.50%,符合率为85.30%(Kappa=0.699)。根据结节大小选择性使用两种方法诊断的敏感度最高,与病理诊断的一致性检验较单一方法更高(Kappa=0.699,P0.01)。结论根据甲状腺结节大小选择性使用固定面积法和实际面积法可以明显提高弹性成像诊断恶性甲状腺结节的敏感性。
[Abstract]:Objective to limit the application of elastic imaging technique in the diagnosis of thyroid nodules due to its poor sensitivity and other adverse factors. This study was based on the elastic strain rate ratio (SR) method. Different SR calculation methods were used for thyroid nodules of different sizes to explore the value of different SR calculation methods in differentiating benign and malignant thyroid nodules. Materials and methods A retrospective analysis of 340 nodules was performed in 336 patients with fine needle puncture of thyroid guided by ultrasound. The criteria of cytopathology combined with follow-up were used. To analyze the difference between fixed area method and real area method in differentiating benign and malignant thyroid nodules. Results among 340 nodules diagnosed by ultrasound, 91 were small nodules and 249 were large nodules. Among 91 cases, 36 cases were malignant, 55 cases were benign, 104 cases were malignant and 145 cases were benign. For the small nodules whose longitudinal and transverse diameters were 鈮，
本文编号：2189374
[Abstract]:Objective to limit the application of elastic imaging technique in the diagnosis of thyroid nodules due to its poor sensitivity and other adverse factors. This study was based on the elastic strain rate ratio (SR) method. Different SR calculation methods were used for thyroid nodules of different sizes to explore the value of different SR calculation methods in differentiating benign and malignant thyroid nodules. Materials and methods A retrospective analysis of 340 nodules was performed in 336 patients with fine needle puncture of thyroid guided by ultrasound. The criteria of cytopathology combined with follow-up were used. To analyze the difference between fixed area method and real area method in differentiating benign and malignant thyroid nodules. Results among 340 nodules diagnosed by ultrasound, 91 were small nodules and 249 were large nodules. Among 91 cases, 36 cases were malignant, 55 cases were benign, 104 cases were malignant and 145 cases were benign. For the small nodules whose longitudinal and transverse diameters were 鈮，
本文编号：2189374
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