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彩色多普勒血流显像对重度锁骨下动脉狭窄的评估

发布时间:2018-08-21 19:38
【摘要】:目的:评价彩色多普勒血流显像(Color doppler flow imagine, CDFI)血流动力学指标对于重度(狭窄率70%-99%)锁骨下动脉狭窄(Subclavian artery stenosis, SAS)的诊断价值。 方法:收集2009年3月至2013年12月疑似为SAS来我院就诊并经数字减影血管造影(Digital subtraction angiography, DSA)证实的患者252例,狭窄程度分为中度狭窄(50%-69%)、重度狭窄(70%-99%)。利用彩色多普勒血流显像,记录锁骨下动脉狭窄段残余管腔直径(Dr)、收缩期峰值流速(PSV1)和舒张末流速(EDV),并记录管径相对正常的狭窄远端原始管腔直径(Do)和收缩期峰值流速(PSV2),计算直径狭窄率(1-Dr/Do)和峰值流速比值(PSV1/PSV2);以DSA检查结果作为参考,通过接收者操作特征曲线(ROC曲线)分析,得出锁骨下动脉重度狭窄(70%-99%)患者上述指标的理想临界值及其诊断价值。 结果:在252例患者中,109例诊断为重度SAS(70%-99%),143例为中度SAS(50%-69%)。评价重度SAS(70%-99%)的指标理想临界值分别为:PSV1≥343cm/s, EDV≥60cm/s, PSV1/PSV2≥4.0;诊断重度SAS(70%-99%)指标准确率分别为:PSV1为86.1%,EDV为85.7%,PSVl/PSV2为84.9%,1-Dr/Do为80.2%。另外,如果PSV1结合EDV和1-Dr/Do作为诊断指标,诊断准确率将从86.1%上升到87.3%;如果PSV1结合EDV和PSV1/PSV2作为诊断指标,诊断准确率将达到95.8%。 结论:彩色多普勒血流显像血流动力学指标PSV1, EDV和PSV1/PSV2在诊断重度SAS(70%-99%)上与DSA具有良好的一致性,联合运用三个指标可以大大提高诊断准确率。
[Abstract]:Objective: to evaluate the diagnostic value of color Doppler flow imaging (Color doppler flow imagine, CDFI) hemodynamics in severe (70-99%) subclavian artery stenosis with (Subclavian artery stenosis, SAS). Methods: from March 2009 to December 2013, 252 patients with suspected SAS who were confirmed by digital subtraction angiography (Digital subtraction angiography, DSA) were divided into moderate stenosis (50-69%) and severe stenosis (70-99%). Using color Doppler flow imaging, (Dr), peak systolic velocity (PSV1) and end-diastolic velocity (EDV),) of residual lumen diameter in the stenosis segment of subclavian artery were recorded. The original lumen diameter (Do) and peak systolic peak velocity (PSV2) of the distal stenosis with normal diameter were recorded. The diameter stenosis rate (1-Dr/Do) was calculated. And peak velocity ratio (PSV1/PSV2). The results of DSA were used as a reference. The ideal critical value and diagnostic value of the above indexes in patients with severe subclavian artery stenosis (70-99%) were obtained by the analysis of the receiver operating characteristic curve (ROC curve). Results: of the 252 cases, 109 cases were diagnosed as severe SAS (70-99%), 143 cases were moderate SAS (50-69%). The ideal critical values for evaluating severe SAS (70-99%) were as follows: PSV1 鈮,

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