早期心尖肥厚型心肌病超声特征的Logistic回归分析

发布时间：2018-08-22 09:51

【摘要】：目的探讨超声诊断早期心尖肥厚型心肌病(PAHCM)的特征性指标。方法对69例疑似PAHCM患者行超声心动图检查,于相应切面测量舒张末期左心室心尖部心肌和左心室后壁心肌的厚度,并计算二者比值。同时观察并记录心尖部心肌回声,心尖部心腔面积变化及心尖部心肌运动情况。采用Logistic回归分析模型分析PAHCM超声特征,并以ROC曲线评价Logistic模型的预报能力。结果左心室心尖部与后壁心肌厚度比值(X1)、左心室心尖部心肌回声(X2)、左心室心尖部心腔面积(X3)为PAHCM的特征性超声指标。Logistic模型:Logit(P)=-3.022+4.474 X1+2.830 X2+3.665 X3。此模型预报正确率为94.20%(65/69),ROC曲线下面积为0.979±0.015。结论左心室心尖部与后壁心肌厚度比值、左心室心尖部心肌回声、左心室心尖部心腔面积可以较精确地预测PAHCM。
[Abstract]:Objective to study the characteristic indexes of (PAHCM) in diagnosing early apical hypertrophic cardiomyopathy by ultrasound. Methods Echocardiography was performed in 69 patients with suspected PAHCM. The thickness of left ventricular apical myocardium and left ventricular posterior wall were measured at the end of diastolic end and the ratio of the two was calculated. At the same time, we observed and recorded the myocardial echo of the apex, the change of the area of the apical heart and the motion of the apical myocardium. The ultrasonic characteristics of PAHCM were analyzed by Logistic regression model, and the prediction ability of Logistic model was evaluated by ROC curve. Results the ratio of left ventricular apical to posterior wall myocardial thickness (X1), left ventricular apical myocardial echo (X2) and left ventricular apical area (X3) were the characteristic ultrasound indexes of PAHCM. Logistic model: logit (P): -3.022 4.474 X 1 2.830 X 2 3.665 X 3. The prediction accuracy of this model is 94.20% (65 / 69) and the area under the ROC curve is 0.979 卤0.015. Conclusion the ratio of left ventricular apical to posterior wall myocardial thickness, left ventricular apical myocardial echo and left ventricular apical area can accurately predict PAHCM.
【作者单位】：中国医科大学附属盛京医院超声科;
【基金】：辽宁省科技厅科学技术计划项目(2013225049)
【分类号】：R542.2;R445.1

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