超声实时组织弹性成像技术评估颈动脉斑块性质的应用研究
发布时间：2018-09-08 14:43
【摘要】：【目的】 本课题是应用实时组织弹性成像（real-time tissue elastography，RTE）技术获得颈动脉斑块动态弹性图，利用计算机辅助程序获得斑块灰阶中位数（gray-scale median，GSM）。对不同灰阶斑块的超声弹性图、弹性评分、弹性参数（包括弹性硬度指数和弹性硬度比值）及GSM作一个初步的了解。 【方法】 1、选取2013年1月至2013年12月在我院进行颈部血管检查患者的85个斑块,来源于40例患者，，男性21例，女性19例，平均年龄57.3±7.5岁。 2、采用GE LOGIQE9超声诊断仪，线阵9L探头，频率5.0～9.0MHZ。对颈动脉斑块进行常规超声及弹性成像检查，获得斑块的二维灰阶图及弹性动态图。 3、根据斑块的动态弹性图获得斑块的弹性评分、弹性参数。利用计算机辅助程序获得斑块的GSM。 4、根据Gray-weale等[1]提出的分类方案将斑块分成四组。分析四组斑块的弹性评分、弹性参数及GSM的差异。 5、分析斑块的弹性参数与斑块的GSM之间的相关性。 【结果】 1、斑块的RTE图表现：均质低回声斑块表现为以均匀的绿色为主；不均质低回声斑块表现为以不均匀绿色为主或不规则绿蓝相间；不均质高回声斑块表现为蓝色为主或不规则蓝绿相间；均质高回声斑块表现为蓝色为主。 2、斑块弹性评分、弹性参数及GSM组间两两比较：均质低回声斑块组与不均质高回声斑块组及均质高回声斑块组间有统计学差异（P0.05）；不均质低回声斑块与不均质高回声斑块组及均质高回声斑块组间有统计学差异（P0.05）。 3、斑块的弹性硬度指数与斑块的GSM成线性关系（r=0.886，P=0.000）；斑块弹性硬度比值与斑块的GSM成线性关系（r=0.810，P=0.000）。 【结论】 1、不同灰阶斑块具有不同特征的RTE图。 2、斑块的弹性评分及弹性参数能够反映不同灰阶斑块的软硬度。 3、斑块的弹性参数与斑块的GSM成线性关系。
[Abstract]:[objective] in this study, real-time tissue elastography (real-time tissue elastography,RTE) was used to obtain dynamic elastic map of carotid plaques, and the median of plaque gray scale (gray-scale median,GSM) was obtained by computer aided program. The ultrasonic elasticity of plaques with different grayscale was evaluated. Elastic parameters (including elastic hardness index and elastic hardness ratio) and GSM were studied. [methods] 1.Eighty-five plaques were selected from January 2013 to December 2013 in our hospital. There were 40 patients (male 21, female 19, mean age 57.3 卤7.52). GE LOGIQE9 ultrasound was used with a linear 9L probe with a frequency of 5.0 ~ 9.0MHZ. Carotid plaques were examined by conventional ultrasound and elastic imaging, and two-dimensional gray-scale and elastic dynamic images of plaques were obtained. 3. According to the dynamic elastic maps of plaques, the elastic scores and elastic parameters of plaques were obtained. The patch GSM. 4 was obtained by computer aided program, and the patch was divided into four groups according to the classification scheme proposed by Gray-weale et al. The elastic scores of plaques in four groups were analyzed. The difference between elastic parameters and GSM. 5. The correlation between the elastic parameters of plaque and GSM of plaque was analyzed. [results] 1. The RTE pattern of plaque showed that homogeneous green was dominant in homogeneous hypoechoic plaque; Heterogeneous hypoechoic plaques were characterized by uneven green or irregular greenish-blue phases, and heterogeneous hyperechoic plaques were mainly blue or irregular blue-green patches. Homogeneous hyperechoic plaque showed blue. 2. Plaque elasticity score, elastic parameter and GSM group were compared: there was significant difference between homogeneous hypoechoic plaque group and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). There was significant difference between heterogeneous hypoechoic plaque and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). 3. The elastic hardness index of plaque was linearly correlated with GSM of plaque (r = 0.886P = 0.000). There was a linear relationship between the ratio of elastic hardness of plaque and the GSM of plaque (r = 0.810 / P = 0.000). [conclusion] 1. The RTE diagram with different gray scale plaques has different characteristics. 2. The elastic score and elastic parameters of plaque can reflect. The soft and hard degree of different gray-scale plaques. 3. The elastic parameters of plaques are linearly related to the GSM of plaques.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1
本文编号：2230829
[Abstract]:[objective] in this study, real-time tissue elastography (real-time tissue elastography,RTE) was used to obtain dynamic elastic map of carotid plaques, and the median of plaque gray scale (gray-scale median,GSM) was obtained by computer aided program. The ultrasonic elasticity of plaques with different grayscale was evaluated. Elastic parameters (including elastic hardness index and elastic hardness ratio) and GSM were studied. [methods] 1.Eighty-five plaques were selected from January 2013 to December 2013 in our hospital. There were 40 patients (male 21, female 19, mean age 57.3 卤7.52). GE LOGIQE9 ultrasound was used with a linear 9L probe with a frequency of 5.0 ~ 9.0MHZ. Carotid plaques were examined by conventional ultrasound and elastic imaging, and two-dimensional gray-scale and elastic dynamic images of plaques were obtained. 3. According to the dynamic elastic maps of plaques, the elastic scores and elastic parameters of plaques were obtained. The patch GSM. 4 was obtained by computer aided program, and the patch was divided into four groups according to the classification scheme proposed by Gray-weale et al. The elastic scores of plaques in four groups were analyzed. The difference between elastic parameters and GSM. 5. The correlation between the elastic parameters of plaque and GSM of plaque was analyzed. [results] 1. The RTE pattern of plaque showed that homogeneous green was dominant in homogeneous hypoechoic plaque; Heterogeneous hypoechoic plaques were characterized by uneven green or irregular greenish-blue phases, and heterogeneous hyperechoic plaques were mainly blue or irregular blue-green patches. Homogeneous hyperechoic plaque showed blue. 2. Plaque elasticity score, elastic parameter and GSM group were compared: there was significant difference between homogeneous hypoechoic plaque group and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). There was significant difference between heterogeneous hypoechoic plaque and heterogeneous hyperechoic plaque group and homogeneous hyperechoic plaque group (P0.05). 3. The elastic hardness index of plaque was linearly correlated with GSM of plaque (r = 0.886P = 0.000). There was a linear relationship between the ratio of elastic hardness of plaque and the GSM of plaque (r = 0.810 / P = 0.000). [conclusion] 1. The RTE diagram with different gray scale plaques has different characteristics. 2. The elastic score and elastic parameters of plaque can reflect. The soft and hard degree of different gray-scale plaques. 3. The elastic parameters of plaques are linearly related to the GSM of plaques.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R445.1
【参考文献】
相关期刊论文 前10条
1 董艳玲;颈动脉粥样硬化与缺血性脑卒中[J];脑与神经疾病杂志;2003年02期
2 贾伟华,田桂玲;颈动脉斑块稳定性的研究进展[J];国外医学(脑血管疾病分册);2004年02期
3 朱娅娟;冯蕾;;实时超声弹性成像技术对颈总动脉粥样硬化斑块稳定性的评估[J];昆明医科大学学报;2013年01期
4 徐智章,俞清;超声弹性成像原理及初步应用[J];上海医学影像;2005年01期
5 俞清,徐智章,毛枫,黄备建,王文平;超声弹性成像在乳腺疾病中的初步应用[J];上海医学影像;2005年02期
6 罗葆明,欧冰,冯霞,周敏,文艳玲;乳腺疾病实时组织弹性成像与病理对照的初步探讨[J];中国超声医学杂志;2005年09期
7 勇强;苏博;;颈动脉不稳定斑块的研究进展[J];中华医学超声杂志(电子版);2009年03期
8 高媛;张宇虹;苏本利;;超声弹性成像技术评价2型糖尿病合并微量白蛋白尿患者颈动脉血管壁弹性变化及其临床意义[J];中华医学超声杂志(电子版);2011年07期
9 王怡,王涌,张希敏,秦茜淼,王意达,徐智章;组织弹性成像鉴别乳腺良恶性肿块的价值评估[J];中国医学影像技术;2005年11期
10 胡莉君;吕清;王新房;王静;贺林;黄君红;段利科;丁灵琳;;超声弹性成像评价2型糖尿病患者颈动脉和肱动脉血管壁弹性[J];中国医学影像技术;2009年03期
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