高频超声筛查甲状旁腺探讨反复发作泌尿系结石与原发性甲状旁腺功能亢进的关系
发布时间：2018-09-13 16:45
【摘要】：目的应用高频超声筛查甲状旁腺探讨泌尿系结石与原发性甲状旁腺功能亢进(PHPT)的关系。方法对200例泌尿系结石患者(结石组)及200例健康体检者(对照组)行甲状旁腺超声扫查,观察甲状旁腺显示情况及病变;并对超声发现异常者行血清甲状旁腺激素(PTH)、血钙、血磷检查。结果结石组中,高频超声显示甲状旁腺136例(136/200,68.00%),发现甲状旁腺肿块28例(28/200,14.00%),肿块体积(588.93±15.25)mm3。对照组中,高频超声显示甲状旁腺90例(90/200,45.00%),发现甲状旁腺肿块4例(4/200,2.00%),肿块体积(84.74±12.51)mm3。两组间高频超声甲状旁腺显示率、甲状旁腺肿块显示率及肿块体积差异均有统计学意义(P均0.05)。结石组12例甲状旁腺肿块患者为PHPT,另16例及对照组4例甲状旁腺肿块患者血清PTH、血钙、血磷均正常。两组间PHPT发生率差异有统计学意义(P0.05)。结石组泌尿系结石发作≥3次者PHPT发生率(7/53,13.21%)高于结石发作3次者(5/147,3.40%;P0.05)。超声显示12例PHPT均为单发肿块;7例接受甲状旁腺切除术,术后病理均为腺瘤;5例接受内科药物治疗。结论 PHPT是反复发作泌尿系结石的一个重要且易被忽略的原因,高频超声可作为反复发作泌尿系结石患者甲状旁腺的常规筛查手段。
[Abstract]:Objective to investigate the relationship between urolithiasis and primary hyperparathyroidism (PHPT) by high frequency ultrasound screening of parathyroid gland. Methods two hundred patients with urolithiasis (stone group) and 200 healthy persons (control group) were examined by ultrasonography to observe the display and pathological changes of parathyroid gland, and the serum parathyroid hormone (PTH), serum calcium was performed in those who were found abnormal by ultrasound. Blood phosphorus test. Results in the calculi group, high frequency ultrasound showed parathyroid gland in 136 cases (136 / 200%), 28 cases of parathyroid mass (28 / 200 ~ 14.00%) and mass volume (588.93 卤15.25) mm3.. In the control group, 90 cases (45.00%) of parathyroid gland were detected by high frequency ultrasound, 4 cases (4 / 2002.00%) of parathyroid mass and (84.74 卤12.51) mm3. of parathyroid mass were found. There were significant differences in the display rate of parathyroid gland, the display rate of parathyroid mass and the volume of mass between the two groups (P 0.05). There were 12 patients with parathyroid mass in the stone group and 16 patients with PHPT, and 4 patients with parathyroid mass in the control group. The serum levels of serum calcium and phosphorus were normal in 12 patients with parathyroid mass and 4 patients in the control group. The incidence of PHPT was significantly different between the two groups (P0.05). The incidence of PHPT in patients with urinary calculi 鈮，
本文编号：2241754
[Abstract]:Objective to investigate the relationship between urolithiasis and primary hyperparathyroidism (PHPT) by high frequency ultrasound screening of parathyroid gland. Methods two hundred patients with urolithiasis (stone group) and 200 healthy persons (control group) were examined by ultrasonography to observe the display and pathological changes of parathyroid gland, and the serum parathyroid hormone (PTH), serum calcium was performed in those who were found abnormal by ultrasound. Blood phosphorus test. Results in the calculi group, high frequency ultrasound showed parathyroid gland in 136 cases (136 / 200%), 28 cases of parathyroid mass (28 / 200 ~ 14.00%) and mass volume (588.93 卤15.25) mm3.. In the control group, 90 cases (45.00%) of parathyroid gland were detected by high frequency ultrasound, 4 cases (4 / 2002.00%) of parathyroid mass and (84.74 卤12.51) mm3. of parathyroid mass were found. There were significant differences in the display rate of parathyroid gland, the display rate of parathyroid mass and the volume of mass between the two groups (P 0.05). There were 12 patients with parathyroid mass in the stone group and 16 patients with PHPT, and 4 patients with parathyroid mass in the control group. The serum levels of serum calcium and phosphorus were normal in 12 patients with parathyroid mass and 4 patients in the control group. The incidence of PHPT was significantly different between the two groups (P0.05). The incidence of PHPT in patients with urinary calculi 鈮，
本文编号：2241754
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