多发性骨髓瘤多种磁共振成像序列图像质量的比较

发布时间：2018-09-17 14:50

【摘要】：目的比较磁共振T1WI脂相、T1WI水相、短时反转恢复(STIR)序列以及弥散加权成像(DWI)序列在评价多发性骨髓瘤(MM)时的图像质量。方法对20例初诊或治疗后随诊的MM患者行冠状位T1WI脂相、T1WI水相、STIR序列及轴位DWI序列扫描,分段评价4个扫描序列的图像质量。测量并计算每个扫描序列的颅骨、脊柱、骨盆、肱骨、股骨、胫腓骨及肋骨处图像的信噪比(SNR)。选取20处MM的活动性病灶,测量并计算每个扫描序列病变部位的强化噪声比(CNR)。结果所有图像质量均在可评价范围内。T1WI脂相、T1WI水相、STIR序列以及DWI序列的平均图像质量评分分别为4.19±0.70、4.16±0.73、3.89±0.70及3.76±0.68,T1WI脂相和水相的图像质量明显优于STIR序列(P=0.000和P=0.001)和DWI序列(P均=0.000),但T1WI脂相及水相之间(P=0.723)、STIR序列及DWI序列之间(P=0.167)差异均无统计学意义。T1WI水相的SNR显著高于T1WI脂相、STIR序列及DWI序列(P均=0.000),而后三者间差异无统计学意义(P均0.05)。DWI序列的CNR均值虽略高于其他3个序列,但4个扫描序列CNR之间差异均无统计学意义(P均0.05)。结论 T1WI脂相、T1WI水相、STIR序列及DWI序列成像各具优势,应联合应用诊断MM。
[Abstract]:Objective to evaluate the image quality of multiple myeloma (MM) by comparing the aqueous phase of Mr T1WI lipid phase T 1WI, the short time inversion recovery (STIR) sequence and the diffusion-weighted (DWI) sequence in the evaluation of multiple myeloma. Methods Twenty patients with MM who had been followed up at first visit or after treatment were examined by using coronal T1WI fat phase T 1WI and axial DWI sequence, and the image quality of 4 sequences was evaluated. The signal-to-noise ratio (SNR) (SNR). For each scan sequence of skull, spine, pelvis, humerus, femur, tibia and fibula, and ribs was measured and calculated. Twenty active lesions of MM were selected and the enhanced noise ratio (CNR).) of each lesion was measured and calculated. Results the average image quality scores of all images were 4.19 卤0.70 卤0.73 卤0.73 卤3.89 卤0.70 and 3.76 卤0.68 / T1WI, respectively, which were significantly better than those of STIR sequence (P0.000, P0. 001) and DWI sequence (P0. 000 and P0. 001). The average image quality scores of all images were 4. 19 卤0. 70 卤0. 73 卤0. 73 and 3. 76 卤0. 68% T1WI respectively (P0. 000, P0. 001) and DWI sequences (P0. 000 and P0. 001). However, there was no significant difference in SNR between T1WI lipid phase and water phase (P0. 723) and DWI sequences (P < 0. 167). The SNR in aqueous phase of T1WI was significantly higher than that in T1WI lipid phase and DWI sequence (P < 0. 05), but there was no significant difference among the three sequences (all P 0. 05) .DWI sequence. Although the mean CNR of the two groups is slightly higher than that of the other three sequences, However, there was no significant difference in CNR among the four scanning sequences (all P 0. 05). Conclusion the contrast sequence and DWI sequence of T1WI on T 1WI have advantages, so it is necessary to use it in the diagnosis of MM..
【作者单位】：中国医学科学院北京协和医学院北京协和医院放射科;
【基金】：国家自然科学基金(81371608) 北京市科技新星项目(Z111107054511127)~~
【分类号】：R445.2;R733.3

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