相位对比法磁共振成像测量主动脉和肺动脉起始部净血流量的准确性研究

发布时间：2018-09-18 08:58

【摘要】：目的采用相位对比法(PC)磁共振成像(MRI)测量健康志愿者的主、肺动脉起始部净血流量,并进行比较,以验证PC MRI测量主、肺动脉起始部净血流量的准确性及可重复性。方法选取2012年1月—2013年12月昆明医科大学第二附属医院进行体检的健康志愿者31例,采用PC MRI测量心动周期内主、肺动脉起始部净血流量,观察PC MRI测量主、肺动脉起始部净血流量的准确性;前后两次测量9例健康志愿者主、肺动脉起始部净血流量,观察PC MRI测量主、肺动脉起始部净血流量的可重复性。结果主、肺动脉起始部时间-净血流量图呈逐渐上升曲线,相对应心脏的收缩期,主、肺动脉起始部净血流量曲线表现为倾斜度较大、光滑且连续的曲线;相对应心脏的舒张期,主、肺动脉起始部净血流量曲线表现为逐渐向上、波形较平缓、光滑且连续的曲线。主动脉起始部净血流量(72.8±12.2)ml,肺动脉起始部净血流量(73.8±13.8)ml,差异无统计学意义(t=-1.924,P=0.64)。主动脉起始部净血流量与肺动脉起始部净血流量呈正相关(r=0.94,P0.05),方程为:Y=-3.825+1.066X。第1次与第2次测量主、肺动脉起始部净血流量比较,差异均无统计学意义(P0.05)。第1次与第2次测量主动脉起始部净血流量呈正相关(r=0.91,P0.05),方程为:Y=-6.669+1.078X。第1次与第2次测量肺动脉起始部净血流量呈正相关(r=0.92,P=0.001),方程为:Y=5.391+0.923X。结论 PC MRI是一种无创、安全、准确、信息量大的检查方法,且不受肺气、骨骼的影响,是研究主、肺动脉起始部净血流量的好方法。
[Abstract]:Objective to evaluate the accuracy and reproducibility of (PC) magnetic resonance imaging (MRI) in measuring the net blood flow at the beginning of the pulmonary artery and the main pulmonary artery in healthy volunteers by using phase contrast method, and to verify the accuracy and reproducibility of the PC MRI measurement of the net blood flow at the beginning of the pulmonary artery. Methods from January 2012 to December 2013, 31 healthy volunteers from the second affiliated Hospital of Kunming Medical University were selected to measure the net blood flow of the main and pulmonary artery in cardiac cycle by PC MRI, and to observe the PC MRI measurement. The accuracy of the net blood flow at the beginning of pulmonary artery and the reproducibility of the measurement of the net blood flow at the beginning of the pulmonary artery by PC MRI were observed in 9 healthy volunteers twice before and after the beginning of the pulmonary artery. Results the time-net blood flow curve of the beginning part of the pulmonary artery showed a gradual ascending curve, and the net blood flow curve of the pulmonary artery at the beginning of the pulmonary artery showed a large inclination, smooth and continuous curve, corresponding to the systolic phase of the heart. Corresponding to the diastolic phase of the heart, the net blood flow curve of the starting part of the main and pulmonary arteries showed a gradual upward, smooth and continuous curve. The net blood flow at the beginning of aorta was (72.8 卤12.2) ml,. There was no significant difference in the net blood flow at the beginning of pulmonary artery (73.8 卤13.8) ml, (t = 1.924). There was a positive correlation between the net blood flow at the beginning of the aorta and the net blood flow at the beginning of the pulmonary artery (r = 0.94, P 0.05). There was no significant difference between the first time and the second time in measuring the net blood flow at the beginning of pulmonary artery (P0.05). There was a positive correlation between the first time and the second time in measuring the net blood flow at the beginning of the aorta (r = 0.91P 0.05), and the equation was: 1: Y-6.669 1.078X. There was a positive correlation between the first time and the second time in measuring the net blood flow at the beginning of pulmonary artery (r = 0.92). Conclusion PC MRI is a noninvasive, safe, accurate and informative method, and it is not affected by lung qi and bone. It is a good method to study the net blood flow in the origin of pulmonary artery.
【作者单位】：昆明医科大学第二附属医院放射科;昆明医科大学第一附属医院心内科;昆明医科大学第二附属医院急诊科;云南农业大学学生处;
【基金】：教育部博士点基金新教师类(20115317120003) 云南省教育厅重点项目(2012Z091)
【分类号】：R445.2;R543.2

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