3T磁敏感加权成像中非帕金森病者黑质“燕尾征”存在普遍性的分析

发布时间：2018-10-09 12:35

【摘要】：【目的】采用3.0T磁敏感加权成像(SWI)分析"燕尾征"在非帕金森病者黑质中存在的普遍性,探讨其缺失对帕金森病(PD)的影像诊断价值。【方法】对60例临床确诊的PD患者(PD组)及非PD志愿者(N-PD组)行3.0 TMR磁敏感加权成像,在幅度图上对N-PD组志愿者黑质内"燕尾征"的形态及数量进行分析,并与PD组患者相应区域影像表现进行对照。【结果】排除脑干病变及运动伪影较大的15例患者后,N-PD组49例(96.08%)均在双侧或单侧黑质致密部后外侧见典型"燕尾征";PD组所有54例(100%)"水滴"后方椭圆形高信号均表现缺失,两组差异有统计学意义(P0.05)。【结论】在3.0T SWI幅度图上非PD者黑质内普遍存在"燕尾征"表现;该征象的缺失对PD的诊断具有极高的灵敏度及特异性。
[Abstract]:[objective] to analyze the prevalence of "swallowtail sign" in the substantia nigra of non-Parkinson 's disease patients by 3.0T magnetic sensitivity weighted imaging (SWI). [methods] 60 patients with PD (PD group) and non PD volunteers (N-PD group) were examined with 3. 0 TMR Mr weighted imaging. The shape and quantity of the "swallowtail sign" in the substantia nigra of N-PD volunteers were analyzed on the amplitude map. [results] Fifteen patients with brain stem disease and larger motor artifact were excluded from brain stem lesions, 49 cases (96.08%) were found in bilateral or unilateral substantia nigra pars compacta posterolateral. [results] typical "swallowtail sign" PD was found in both sides and unilateral substantia nigra densification posterolateral in 49 cases (96.08%) of posterior N-PD patients who excluded brainstem lesions and larger motor artifacts. In all 54 cases (100%) of the group, the hyperintensity of oval hyperintensity in the rear of the "water drop" was absent. There was significant difference between the two groups (P0.05). [conclusion] the "swallowtail sign" was common in the substantia nigra of non-PD patients on 3.0T SWI amplitude map, and the absence of this sign was highly sensitive and specific for the diagnosis of PD.
【作者单位】：湖北医药学院附属襄阳医院影像科;湖北医药学院附属襄阳医院神经内科;
【基金】：襄阳市科技计划研究与并发项目(襄科业201411)
【分类号】：R742.5;R445.2

【参考文献】