应用磁共振组织追踪技术评价左室心肌力学参数的研究
发布时间：2018-10-21 15:21
【摘要】：目的:采用心脏磁共振组织追踪技术(CMR-TT)测量健康成年人左室整体和局部心肌力学参数,并探讨其性别和年龄差异。方法:连续选取2015年10月至2016年8月于乌尔姆大学医院(德国)进行1.5T CMR检查的健康成年人共100名,其中男、女性分别为50名,各性别组分别纳入≤50岁和50岁者25名。同时,将100名健康成年人分为低年龄组(≤50岁)和高年龄组(50岁)。进行稳态自由进动序列(SSFP)成像并半自动地勾画左室心内、外膜位置后,使用CVI42软件提供的CMR-TT技术测量左室整体和基底段、中间段和心尖段心肌的径向、周向和纵向应变、应变率、位移、位移速度、(标准化的)扭转和扭转率峰值,采用t检验或非参数检验比较其性别和年龄差异。结果:(1)女性整体和局部心肌应变、应变率大于男性;(2)女性整体和中间段心肌纵向位移速度及中间段心肌纵向位移大于男性;(3)高年龄组整体和局部心肌应变大于低年龄组,周向和纵向舒张期应变率小于低年龄组;(4)高年龄组整体和局部心肌径向位移水平大于低年龄组,纵向舒张期位移速度小于低年龄组;(5)扭转、扭转率无性别和年龄差异。结论:心脏磁共振组织追踪技术可以瞬时定量检测心肌各部分的心肌力学水平,尤其是在评估应变和应变率方面具有优势性。此外,左室整体和局部的部分力学参数存在性别和年龄差异。
[Abstract]:Aim: to measure the global and local myocardial mechanical parameters of left ventricle in healthy adults by cardiac magnetic resonance tissue tracing (CMR-TT), and to explore the gender and age differences. Methods: a total of 100 healthy adults were selected from October 2015 to August 2016 for 1.5T CMR examination at Ulm University Hospital (Germany), including 50 males and 50 females, and 25 healthy adults aged less than 50 years and 50 years old in each sex group, respectively. At the same time, 100 healthy adults were divided into low age group (鈮，
本文编号：2285511
[Abstract]:Aim: to measure the global and local myocardial mechanical parameters of left ventricle in healthy adults by cardiac magnetic resonance tissue tracing (CMR-TT), and to explore the gender and age differences. Methods: a total of 100 healthy adults were selected from October 2015 to August 2016 for 1.5T CMR examination at Ulm University Hospital (Germany), including 50 males and 50 females, and 25 healthy adults aged less than 50 years and 50 years old in each sex group, respectively. At the same time, 100 healthy adults were divided into low age group (鈮，
本文编号：2285511
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