超声弹性成像与常规超声对甲状腺结节诊断价值的Meta分析

发布时间：2018-10-30 09:56

【摘要】：目的采用Meta分析评价超声弹性成像及常规超声对甲状腺结节的诊断价值。资料与方法以"超声弹性成像、常规超声、甲状腺结节、elastosonography、ultrasonography、thyroid nodules"为检索词检索1980-2013年中国知网、万方数据库、OVID、Cochrane图书馆、Pub Med、Embase等数据库收录的文献。选取应用超声弹性成像及常规超声诊断甲状腺结节的临床研究,对符合要求的文献进行质量评价和异质性检验,汇总合并特异度和敏感度,并进行综合ROC曲线分析。结果共纳入14篇文献,其中中文10篇,英文4篇。异质性检验发现常规超声与超声弹性成像、两者联合诊断的敏感度均存在异质性。常规超声、超声弹性成像及两者联合的合并敏感度分别为0.82(95%CI 0.79~0.85)、0.61(95%CI 0.57~0.64)、0.93(95%CI0.90~0.95),合并特异度分别为0.70(95%CI 0.68~0.72)、0.84(95%CI 0.82~0.86)、0.69(95%CI 0.67~0.72),综合ROC曲线下面积分别为0.8549、0.8925、0.9614。纳入文献稳定性好。结论超声弹性成像诊断甲状腺结节的良恶性优于常规超声,两者联合诊断效果更好。
[Abstract]:Objective to evaluate the diagnostic value of ultrasound elastic imaging and conventional ultrasound in thyroid nodules by Meta analysis. Materials and methods using "Ultrasonic Elastic Imaging, conventional Ultrasound, thyroid nodule, elastosonography,ultrasonography,thyroid nodules" as the key words, we searched the literature collected from China Zhiwang, Wanfang Database, OVID,Cochrane Library, Pub Med,Embase and other databases from 1980 to 2013. The clinical study of ultrasonic elastic imaging and conventional ultrasound in the diagnosis of thyroid nodules was carried out to evaluate the quality and heterogeneity of the literature and to sum up the combined specificity and sensitivity, and to analyze the comprehensive ROC curve. Results A total of 14 articles were included, including 10 in Chinese and 4 in English. Heterogeneity test showed that conventional ultrasound and ultrasonic elastic imaging had heterogeneity in the sensitivity of the combined diagnosis. The combined sensitivity of conventional ultrasound, ultrasonic elastic imaging and their combination were 0.82 (95%CI 0.79 0.85), 0.61 (95%CI 0.57 卤0.64), 0.93 (95%CI0.90~0.95), respectively. The combined specificity was 0.70 (95%CI 0.680.72), 0.84 (95%CI 0.82N 0.86), 0.69 (95%CI 0.67C 0.72), respectively. The area under the comprehensive ROC curve was 0.85490.8925U 0.9614, respectively. The stability of the literature is good. Conclusion Ultrasound elastography is superior to conventional ultrasonography in the diagnosis of benign and malignant thyroid nodules.
【作者单位】：伊犁哈萨克自治州友谊医院超声科;新疆医科大学第三附属医院超声二科;
【分类号】：R445.1;R581

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