比较钆塞酸二钠和钆喷酸葡胺增强MRI检查对乙肝肝硬化背景肝癌的诊断价值
发布时间：2018-11-28 14:11
【摘要】：目的探讨钆塞酸二钠(Gd-EOB-DTPA)MR扫描对乙肝肝硬化背景肝癌的诊断价值。方法 32例乙肝肝硬化患者共34个肝癌病灶,均行两种MR成像[模式1:T2WI、DWI、T1WI同反相位、Gd-DTPA动态增强(平扫、动脉期、门静脉期及延迟期);模式2:T2WI、DWI、T1WI同反相位、Gd-EOB-DTPA动态增强(平扫、动脉期、门静脉期、延迟期及肝胆期)]。由2名阅片者采用双盲法分析图像,记录病灶的信号特点、强化方式及阅片者的信心评分。比较两种成像模式下阅片者诊断肝癌信心评分、一致性、ROC曲线下的面积、敏感性及阳性预测值。结果 (1)模式2下两位阅片者诊断肝癌的信心评分均提高,差异有统计学意义(P0.05);且2名阅片者在模式2下诊断肝癌的一致性均增加。(2)2名阅片者在模式2下诊断肝癌的ROC曲线下面积均较模式1增加,差异有统计学意义(P0.05)。(3)2名阅片者在模式2下诊断肝癌的敏感性较模式1均提高,差异有统计学意义(P0.05),阳性预测值差异均无统计学意义(P0.05)。结论 Gd-EOB-DTPA MR扫描有助于提高阅片者对乙肝肝硬化背景肝癌的诊断信心从而提高诊断能力。
[Abstract]:Objective to evaluate the diagnostic value of gadolinium disodium (Gd-EOB-DTPA) MR scan in background liver cancer of hepatitis B cirrhosis. Methods Thirty-four liver cancer lesions were performed in 32 patients with hepatitis B cirrhosis. Two kinds of MR imaging were performed [1: T2WIWI DWI T1WI, Gd-DTPA dynamic enhancement (plain scan, arterial phase, portal vein phase and delayed phase); In mode 2: T2WI / DWII T1WI, Gd-EOB-DTPA was enhanced dynamically (plain scan, arterial phase, portal vein phase, delayed phase and hepatobiliary phase). The image was analyzed by double blind method, and the signal characteristics, enhancement mode and confidence score of the film reader were recorded. The confidence score, consistency, area under ROC curve, sensitivity and positive predictive value were compared between the two imaging models. Results (1) under Mode 2, the confidence scores of the two radiographers in diagnosing liver cancer increased significantly (P0.05). The area under the ROC curve of the two radiographs under mode 2 was higher than that of the model 1, and the consistency of diagnosis of HCC in mode 2 was higher than that in mode 2. (2) the area under the ROC curve of the two radiographs in the diagnosis of HCC under mode 2 was higher than that in mode 1. The difference was statistically significant (P0.05). (3). The sensitivity of 2). (readers in the diagnosis of liver cancer in mode 2 was higher than that in mode 1. The difference was statistically significant (P0.05), and there was no significant difference in positive predictive value (P0.05). Conclusion Gd-EOB-DTPA MR scan is helpful to improve the diagnostic confidence of Hepatitis B cirrhotic background liver cancer and improve the diagnostic ability.
【作者单位】： 南通大学附属南通第三医院影像科;
【基金】：南通市科技局社会发展项目(编号:S2013141) 南通市卫生局青年基金课题项目(编号:WQ2014039)
【分类号】：R445.2;R735.7
[Abstract]:Objective to evaluate the diagnostic value of gadolinium disodium (Gd-EOB-DTPA) MR scan in background liver cancer of hepatitis B cirrhosis. Methods Thirty-four liver cancer lesions were performed in 32 patients with hepatitis B cirrhosis. Two kinds of MR imaging were performed [1: T2WIWI DWI T1WI, Gd-DTPA dynamic enhancement (plain scan, arterial phase, portal vein phase and delayed phase); In mode 2: T2WI / DWII T1WI, Gd-EOB-DTPA was enhanced dynamically (plain scan, arterial phase, portal vein phase, delayed phase and hepatobiliary phase). The image was analyzed by double blind method, and the signal characteristics, enhancement mode and confidence score of the film reader were recorded. The confidence score, consistency, area under ROC curve, sensitivity and positive predictive value were compared between the two imaging models. Results (1) under Mode 2, the confidence scores of the two radiographers in diagnosing liver cancer increased significantly (P0.05). The area under the ROC curve of the two radiographs under mode 2 was higher than that of the model 1, and the consistency of diagnosis of HCC in mode 2 was higher than that in mode 2. (2) the area under the ROC curve of the two radiographs in the diagnosis of HCC under mode 2 was higher than that in mode 1. The difference was statistically significant (P0.05). (3). The sensitivity of 2). (readers in the diagnosis of liver cancer in mode 2 was higher than that in mode 1. The difference was statistically significant (P0.05), and there was no significant difference in positive predictive value (P0.05). Conclusion Gd-EOB-DTPA MR scan is helpful to improve the diagnostic confidence of Hepatitis B cirrhotic background liver cancer and improve the diagnostic ability.
【作者单位】： 南通大学附属南通第三医院影像科;
【基金】：南通市科技局社会发展项目(编号:S2013141) 南通市卫生局青年基金课题项目(编号:WQ2014039)
【分类号】：R445.2;R735.7
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