三维斑点追踪成像技术评价左心室心肌致密化不全患者左心室收缩功能

发布时间：2018-12-11 17:37

【摘要】：目的:应用超声三维斑点追踪成像技术(3D-STE)评价左心室心肌致密化不全(LVNC)患者左心室整体及局部心肌收缩功能。方法:对31例LVNC患者(LVNC组)及31名健康志愿者(对照组)行超声检查,采集三维全容积图像并分析,测量常规超声心动图指标与左心室整体及各节段面积应变(GAS/AS)、纵向应变(GLS/LS)、径向应变(GRS/RS)、圆周应变(GCS/CS),并进行组间及组内比较。采用Pearson相关分析检验GAS与各指标间相关性。结果:1与对照组相比较,LVNC组左心室舒张末期内径(LVEDD)、左心室舒张末期容积(EDV)、左心室收缩末期容积(ESV)、左心室球形指数(SPI)值均增加,舒张末期室间隔厚度(IVSd)、舒张末期左心室厚壁厚度(LVPWD)、射血分数(EF)值均减低(P均0.01)。2与对照组相比较,LVNC组左心室GAS、GLS、GRS、GCS均减低(P均0.01)。3LVNC组非致密节段心肌(心尖及乳头肌水平)较同一水平致密节段心肌AS、LS、RS、CS均减低(P均0.05)。4LVNC患者GAS与EF呈正相关,与EDV、ESV、SPI呈负相关。结论:LVNC患者左心室整体及局部心肌收缩功能减低,且以非致密节段心肌收缩功能减低更为明显,应用超声3D-STE可对LVNC患者左心室局部心肌功能进行定量评价。
[Abstract]:Aim: to evaluate the global and local systolic function of left ventricle in patients with (LVNC) with left ventricular densification by three dimensional speckle tracing imaging (3D-STE). Methods: 31 patients with LVNC (LVNC group) and 31 healthy volunteers (control group) were examined by ultrasound. The three-dimensional full-volume images were collected and analyzed. The indexes of conventional echocardiography and the regional area strain (GAS/AS) of the left ventricle were measured. Longitudinal strain (GLS/LS), radial strain (GRS/RS) and circumferential strain (GCS/CS) were compared. Pearson correlation analysis was used to test the correlation between GAS and each index. Results: 1 compared with the control group, left ventricular end-diastolic diameter (LVEDD), left ventricular end-diastolic volume (EDV), left ventricular end-systolic volume (ESV),) and left ventricular spherical index (SPI) increased in LVNC group. End diastolic septal thickness (IVSd),) left ventricular thick wall thickness (LVPWD),) ejection fraction (EF) decreased at the end of diastolic period (P0.01). 2 compared with control group, left ventricular GAS,GLS,GRS, in LVNC group was significantly lower than that in control group. GCS was decreased (P0. 01). The AS,LS,RS,CS of non-compact segment myocardium (apical and papillary muscle) in 3LVNC group was lower than that in the same level (P0. 05). There was a positive correlation between GAS and EF in 4LVNC patients, and there was a positive correlation between GAS and EDV,ESV,. SPI was negatively correlated. Conclusion: the global and local left ventricular systolic function in patients with LVNC is decreased, especially in non-compact segments. Echocardiographic 3D-STE can be used to quantitatively evaluate the left ventricular regional myocardial function in LVNC patients.
【作者单位】：中国医科大学附属盛京医院超声科;
【分类号】：R542.2;R445.1

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