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肝脏上皮样血管内皮瘤的影像特征及病理基础

发布时间:2019-02-28 08:40
【摘要】:目的:提高对肝脏上皮样血管内皮瘤(EHE)的影像及病理学认识。方法:回顾性分析4例肝EHE的临床及影像学表现,所有病例经过穿刺活检或手术病理学证实。其中3例行CT平扫及增强扫描,1例同时行CT平扫和MRI平扫及增强扫描。结果:CT平扫示肝脏单发或多发类圆形低密度灶,边界清楚,增强扫描呈渐进性轻度强化,中央更低密度区无强化。MRI显示肝内多个环形病灶,实质部分呈稍长T1、稍长T2信号,中央部分呈稍短T1长T2信号,增强扫描示环形实质部分强化、延时扫描示病灶持续强化,结节中央无强化。组织学示肿瘤中部分区域纤维结缔组织增生,其间可见上皮样细胞,呈印戒状。免疫组化,CD34、CD31、Ⅷ因子相关抗原均呈阳性。结论 :肝脏EHE的影像表现具有一定的特征性,表现为单发或多发病灶,病灶之间可相互融合,多发位于肝包膜下,可见"包膜回缩征",增强扫描呈渐进性强化,部分病灶可见"棒棒糖征"。
[Abstract]:Objective: to improve the image and pathology of hepatic epithelioid angioendothelioma (EHE). Methods: the clinical and imaging findings of 4 cases of hepatic EHE were retrospectively analyzed. All cases were confirmed by biopsy or pathology. CT plain scan and contrast enhanced scan were performed in 3 cases, and CT plain scan and MRI plain scan and enhanced scan were performed in 1 case at the same time. Results: CT plain scan showed single or multiple round low density foci of liver with clear boundary, progressive slight enhancement on enhancement scan, and no enhancement in central lower density area. MRI showed multiple circular lesions in the liver, and the parenchyma showed slightly longer T 1, T 1 and T 1, respectively. A slightly longer T 2 signal intensity was seen in the central part of the lesion, and a shorter T 1 long T 2 signal was seen in the central part of the lesion. The circular parenchyma was enhanced by contrast enhanced scan, while the focus was continuously enhanced by delayed scan. Histologically, the fibrous connective tissue was proliferated in some areas of the tumor, and epithelial-like cells were seen in the tumor, showing imprint-like cells. Immunohistochemical staining and CD34,CD31, 鈪,

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