超声弹性成像联合BI-RADS-US分类在老年乳腺癌诊断中的应用价值研究
发布时间：2019-03-28 06:01
【摘要】：目的： 讨论联合应用超声弹性成像评分法和BI-RADS-US分类在乳腺癌诊断中的应用价值。 方法： 研究方法：在2012年1月至2014年4月间,选择来医院乳腺病科就诊的老年乳腺占位患者93例共计127个肿块作为研究对象,患者平均年龄为(68.46±11.51)岁,所有患者均具有最终手术或穿刺而获得的病理结果。对所有入组患者联合应用超声弹性成像评分法和BI-RADS-US分类检查进行诊断,以乳腺铝靶检查为对照组,经病理证实,比较诊断效果。 超声检查方法：患者取正常仰卧位,充分暴露双乳及腋下,应用GE E9超声仪实时线阵高频探头,探头频率6-15MHz。首先进行常规超声检查(包括二维、彩色多普勒、频谱多普勒超声),观察病灶内部回声、后方回声、形态、边界、测量大小、纵横比,了解血供情况,测量血流阻力指数RI。然后启动弹性成像程序,采用实时双幅模式,弹性成像采用评分法进行诊断,同时结合BI-RADS-US分类方法对病灶进行半定量诊断评价。 钼靶检查方法：患者取立位,乳腺钼靶X线摄影的仪器为美国通用GEApha ST MGF-101型乳腺钼靶,对患者两侧乳腺内外斜位摄影采用轴位及斜位投照,部分病例加照侧位片或病灶局部片通过转化变为数字化影像后进行处理。 结果： 1.超声弹性成像评分法和BI-RADS-US分类二者联合应用在乳腺占位判定良恶性分级诊断的灵敏度为84.44%,特异度为89.02%,采用χ2检验分析后,(χ2=67.274,P=0.000),结果具有统计学意义。 2.良恶性肿瘤的二者联合应用,评价诊断分级图像与二维图像面积比(t=5.694,P=0.001)也具有统计学意义。 3.超声弹性成像评分法和BI-RADS-US分类二者联合应用在乳腺占位病变中的诊断符合率高于乳腺钼靶检查。 结论： 超声弹性成像评分法与BI-RADS-US分类联合运用,对病灶进行综合评价,能够有助于老年乳腺肿块患者的良恶性的判定,提高乳腺肿块的诊断准确性。
[Abstract]:Objective: to discuss the value of combined ultrasonic elastography and BI-RADS-US classification in the diagnosis of breast cancer. Methods: from January 2012 to April 2014, 93 elderly patients with breast space occupying lesions were selected as the subjects. The average age of the patients was (68.46 卤11.51) years old, and the mean age of the patients was (68.46 卤11.51) years old, and the average age of the patients was (68.46 卤11.51) years old. All patients had final surgical or puncture results. All the patients in the group were diagnosed by ultrasonic elastography and BI-RADS-US classification. The breast aluminum target examination was used as the control group, and the diagnosis results were compared by pathology. Methods: the patients were taken from normal supine position and exposed to both breast and armpit. The real-time linear array high-frequency probe with GE E9 ultrasonic instrument was used, the frequency of probe was 6-15MHz. First, routine ultrasonography (including 2-D, color Doppler, spectrum Doppler) was performed to observe the internal echo, posterior echo, shape, boundary, measurement size, aspect ratio, blood supply and resistance index of blood flow (RI.). Then the elastic imaging program was started, the real-time double-amplitude mode was used, the elastic imaging was diagnosed by the scoring method, and the semi-quantitative diagnosis of the lesion was carried out with BI-RADS-US classification method at the same time. Mammography: the mammography instrument for mammography was GEApha ST MGF- 101 mammography. Axial and oblique mammography of both sides of the breast were used in the mammography of both sides of the patients, and the mammography of both sides of the breast was performed on both sides of the breast with axial and oblique projection. In some cases, lateral radiographs or local radiographs were transformed into digital images and processed. Results: 1. The sensitivity and specificity of ultrasonic elastography and BI-RADS-US classification were 84.44% and 89.02%, respectively. After analysis by 蠂 2 test, the sensitivity and specificity were 84.44% and 89.02%, respectively (蠂 2 = 67.274, P < 0.000), and the sensitivity and specificity were 84.44% and 89.02%, respectively. The results were statistically significant. 2. In combination with benign and malignant tumors, the area ratio (t = 5.694, P = 0.001) was also statistically significant in the evaluation of diagnostic grading images and two-dimensional images (t = 5.694, P < 0.001). 3. The coincidence rate of ultrasonic elastography and BI-RADS-US classification in the diagnosis of breast space occupying lesions was higher than that of mammography. Conclusion: the combined use of ultrasonic elastic imaging score and BI-RADS-US classification can help the diagnosis of benign and malignant breast masses in elderly patients and improve the accuracy of diagnosis of breast masses.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.9;R445.1
本文编号：2448602
[Abstract]:Objective: to discuss the value of combined ultrasonic elastography and BI-RADS-US classification in the diagnosis of breast cancer. Methods: from January 2012 to April 2014, 93 elderly patients with breast space occupying lesions were selected as the subjects. The average age of the patients was (68.46 卤11.51) years old, and the mean age of the patients was (68.46 卤11.51) years old, and the average age of the patients was (68.46 卤11.51) years old. All patients had final surgical or puncture results. All the patients in the group were diagnosed by ultrasonic elastography and BI-RADS-US classification. The breast aluminum target examination was used as the control group, and the diagnosis results were compared by pathology. Methods: the patients were taken from normal supine position and exposed to both breast and armpit. The real-time linear array high-frequency probe with GE E9 ultrasonic instrument was used, the frequency of probe was 6-15MHz. First, routine ultrasonography (including 2-D, color Doppler, spectrum Doppler) was performed to observe the internal echo, posterior echo, shape, boundary, measurement size, aspect ratio, blood supply and resistance index of blood flow (RI.). Then the elastic imaging program was started, the real-time double-amplitude mode was used, the elastic imaging was diagnosed by the scoring method, and the semi-quantitative diagnosis of the lesion was carried out with BI-RADS-US classification method at the same time. Mammography: the mammography instrument for mammography was GEApha ST MGF- 101 mammography. Axial and oblique mammography of both sides of the breast were used in the mammography of both sides of the patients, and the mammography of both sides of the breast was performed on both sides of the breast with axial and oblique projection. In some cases, lateral radiographs or local radiographs were transformed into digital images and processed. Results: 1. The sensitivity and specificity of ultrasonic elastography and BI-RADS-US classification were 84.44% and 89.02%, respectively. After analysis by 蠂 2 test, the sensitivity and specificity were 84.44% and 89.02%, respectively (蠂 2 = 67.274, P < 0.000), and the sensitivity and specificity were 84.44% and 89.02%, respectively. The results were statistically significant. 2. In combination with benign and malignant tumors, the area ratio (t = 5.694, P = 0.001) was also statistically significant in the evaluation of diagnostic grading images and two-dimensional images (t = 5.694, P < 0.001). 3. The coincidence rate of ultrasonic elastography and BI-RADS-US classification in the diagnosis of breast space occupying lesions was higher than that of mammography. Conclusion: the combined use of ultrasonic elastic imaging score and BI-RADS-US classification can help the diagnosis of benign and malignant breast masses in elderly patients and improve the accuracy of diagnosis of breast masses.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R737.9;R445.1
【共引文献】
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2 潘虹;射频消融治疗59例结直肠癌肝转移的回顾性研究[D];浙江大学;2014年
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