细针穿刺细胞学检查在不同大小甲状腺结节中的应用价值
发布时间：2019-06-21 11:28
【摘要】：目的： 评价甲状腺结节大小对细针穿刺细胞学(FNAC)诊断准确性的影响。 方法： 分析我院2010年6月至2012年10月超声诊断为甲状腺结节的住院手术患者630例,共691个甲状腺结节,收集术前超声引导下细针穿刺细胞学(FNAC)检查的资料,依据Bethesda System细胞学分类方法,将细胞学结果分为Ⅵ级：良性、细胞不足或无法诊断、不典型增生、滤泡性肿瘤、可疑恶性及恶性6个级别,以大于Ⅳ级作为诊断甲状腺恶性肿瘤标准,结节大小按长径(L)分：A组(L0.5cm)、B组(0.5cmL1.0cm)、 C组(L1.Ocm),以术后病理结果为诊断金标准。分别计算出各组超声引导下细针穿刺细胞学对甲状腺结节鉴别诊断的敏感性、特异性、准确率、阴性预测值、阳性预测值、假阴性率及假阳性率。 结果： 691个结节中A组176个(25.47%),B组298个(43.13%),C组217个(31.40%),三组间比较,B组超声引导下FNAC诊断甲状腺结节的准确率(90.94%)明显高于A组(80.11%)与C组(83.41%),差异具有统计学意义(P0.05),A组与C组间的差异无统计学意义(P0.05)；而三组间特异性、阴性预测值、阳性预测值的差异无统计学意义(P0.05)。 结论： 甲状腺结节大小在一定程度上会影响超声引导下细针穿刺细胞学诊断的准确
[Abstract]:Purpose: Evaluation of the accuracy of thyroid nodule size in the diagnosis of fine needle aspiration cytology (FNAC) In response. Methods:630 patients with thyroid nodules from June 2010 to October 2012 were analyzed. A total of 691 thyroid nodules were collected. The cytologic results were divided into grade VI: benign, insufficient or undiagnosed, atypical hyperplasia, follicular tumor, suspicious malignant and malignant 6 levels, and the nodule size was divided by length-diameter (L): Group A (L0 (5 cm), group B (0.5 cmL1.0 cm) and group C (L1. Ocm). The sensitivity, specificity, accuracy, negative predictive value, positive predictive value and false negative rate for the differential diagnosis of thyroid nodules were calculated. and false positive Results:176 (25.47%),298 (43.13%),217 (31.40%) in group A, and 217 (31.40%) in group C. The accuracy of FNAC in the diagnosis of thyroid nodules (90.94%) was significantly higher in group B than in group A (80.11%) and C. There was no significant difference between group A and group C (P0.05). The difference between group A and group C was not statistically significant (P0.05), while the difference between the three groups, negative predictive value and positive predictive value was not statistically significant (P0.05). meaning ( Conclusion: The size of the thyroid nodules will affect the ultrasound in a certain extent.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R581.3;R445.1
本文编号：2504045
[Abstract]:Purpose: Evaluation of the accuracy of thyroid nodule size in the diagnosis of fine needle aspiration cytology (FNAC) In response. Methods:630 patients with thyroid nodules from June 2010 to October 2012 were analyzed. A total of 691 thyroid nodules were collected. The cytologic results were divided into grade VI: benign, insufficient or undiagnosed, atypical hyperplasia, follicular tumor, suspicious malignant and malignant 6 levels, and the nodule size was divided by length-diameter (L): Group A (L0 (5 cm), group B (0.5 cmL1.0 cm) and group C (L1. Ocm). The sensitivity, specificity, accuracy, negative predictive value, positive predictive value and false negative rate for the differential diagnosis of thyroid nodules were calculated. and false positive Results:176 (25.47%),298 (43.13%),217 (31.40%) in group A, and 217 (31.40%) in group C. The accuracy of FNAC in the diagnosis of thyroid nodules (90.94%) was significantly higher in group B than in group A (80.11%) and C. There was no significant difference between group A and group C (P0.05). The difference between group A and group C was not statistically significant (P0.05), while the difference between the three groups, negative predictive value and positive predictive value was not statistically significant (P0.05). meaning ( Conclusion: The size of the thyroid nodules will affect the ultrasound in a certain extent.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R581.3;R445.1
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