以全氟丙烷人血白蛋白微球注射液为造影剂的增强超声检查在肝脏占位性病变性质判断中的应用

发布时间：2019-08-17 11:12

【摘要】：目的以全氟丙烷人血白蛋白微球注射液为造影剂的增强超声检查诊断肝脏占位性病变的良恶性。方法40例"肝占位性病变"患者,均接受常规二维超声检查、以全氟丙烷人血白蛋白微球注射液为造影剂的增强超声检查和增强CT检查。以术后病理结果为金标准,对上述3种检查结果进行比较。结果 40例患者中38例有病理结果,共检出44个病灶(良性病灶5个、恶性病灶39个)。常规二维超声诊断肝脏占位性病变良恶性的准确性为68.4%、敏感性为92.6%、特异性为9.1%、阴性预测值为33%、阳性预测值为71.4%;增强超声分别为92.1%、100.0%、50.0%、100.0%、91.4%;增强CT分别为89.5%、96.7%、40.0%、66.7%、91.4%。增强超声与常规二维超声比较,P0.05;但与增强CT比较差异无统计学意义。结论以全氟丙烷人血白蛋白微球注射液为造影剂的增强超声检查诊断肝脏占位性病变的良恶性优于常规二维超声,与增强CT相当。
[Abstract]:Objective to diagnose benign and malignant liver space-occupying lesions by enhanced ultrasound with perfluoropropane human blood albumin microspheres injection as contrast agent. Methods 40 patients with liver space-occupying lesions were examined by conventional two-dimensional ultrasound. Perfluoropropane human albumin microspheres injection was used as contrast agent for enhanced ultrasound and enhanced CT. According to the postoperative pathological results as the gold standard, the above three kinds of examination results were compared. Results among 40 cases, 38 cases had pathological results and 44 lesions (5 benign lesions and 39 malignant lesions) were detected. The accuracy of conventional two-dimensional ultrasound in the diagnosis of benign and malignant liver space-occupying lesions was 68.4%, the sensitivity was 92.6%, the specificity was 9.1%, the negative predictive value was 33%, the positive predictive value was 71.4%, the enhanced ultrasound was 92.1%, 100.0%, 100.0%, 100.0%, 91.4%, and the enhanced CT was 89.5%, 96.7%, 40.0%, 66.7%, 91.4%, respectively. There was no significant difference between enhanced ultrasound and conventional two-dimensional ultrasound (P 0.05), but there was no significant difference between enhanced ultrasound and enhanced CT. Conclusion enhanced ultrasound with perfluoropropane human albumin microspheres injection as contrast agent is superior to conventional two-dimensional ultrasound in the diagnosis of liver space-occupying lesions, which is similar to enhanced CT.
【作者单位】：第二军医大学附属东方肝胆外科医院;
【分类号】：R445.1;R735.7

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