妊娠早期血浆同型半胱氨酸水平与早产的关系研究
发布时间:2018-01-03 22:36
本文关键词:妊娠早期血浆同型半胱氨酸水平与早产的关系研究 出处:《吉林医学》2016年12期 论文类型:期刊论文
【摘要】:目的:探讨孕早期同型半胱氨酸(Hcy)水平与早产的关系,为早产的预防提供理论依据。方法:以179例早产和足月产孕妇为研究对象,在孕早期测量孕妇同型半胱氨水平,分析孕早期Hcy水平与早产的关系。结果:早产组Hcy水平为(7.81±3.12)μmol/L,足月产组孕早期Hcy水平为(6.73±2.65)μmol/L,足月产组孕早期Hcy水平显著低于早产组,差异有显著性统计学意义(t=2.536,P=0.013)。以孕早期Hcy水平7.53μmol/L作为高水平,以Hcy水平≤7.53μmol/L作为低水平组,OR=2.04(95%CI=1.18~3.54);调整叶酸补充、年龄、孕次和产次后OR=1.76(95%CI=1.24~2.28)。结论:孕早期高水平同型半胱氨酸是早产风险的影响因素,可早期进行监测预防早产。
[Abstract]:Objective: to investigate the relationship between the level of homocysteine cysteine in early pregnancy and preterm delivery, and to provide theoretical basis for the prevention of premature delivery. Methods: 179 pregnant women with preterm and term delivery were studied. The level of homotypic cysteamine was measured in early pregnancy, and the relationship between the level of Hcy and preterm delivery was analyzed. Results: the Hcy level of premature delivery group was 7.81 卤3.12 渭 mol/L. The level of Hcy was 6.73 卤2.65 渭 mol / L in term delivery group, and the level of Hcy in term birth group was significantly lower than that in preterm delivery group. The difference was statistically significant (P < 0.05). The level of Hcy in early pregnancy was 7.53 渭 mol/L. The Hcy level 鈮,
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