间苯三酚与硫酸镁治疗晚期先兆流产的Meta分析

发布时间：2018-01-07 10:38

  本文关键词：间苯三酚与硫酸镁治疗晚期先兆流产的Meta分析　出处：《中华临床医师杂志(电子版)》2016年21期 　论文类型：期刊论文

  更多相关文章： 间苯三酚 硫酸镁 晚期先兆流产 Meta分析

【摘要】：目的系统分析比较间苯三酚及硫酸镁在晚期先兆流产中的疗效。方法检索中国生物医学文献数据库、万方、知网、维普、百度等国内中文数据库收录的公开发表与研究目的相关的随机对照研究文献,应用Rev Man 5.3软件对满足条件的数据进行合并分析,对两组药物治疗起效时间、宫缩缓解时间、保胎的有效率以及不同方法的不良反应发生率进行分析比较。结果 6个随机对照试验纳入研究分析。间苯三酚与硫酸镁组相比,治疗起效时间晚0.75 h,95%可信区间为0.25~1.24,两组宫缩缓解时间无统计学差异(P=0.5),硫酸镁相比,间苯三酚治疗先兆流产有效率的RR值为1.09(95%可信区间为1.03~1.16),不良反应的RR值为0.02(95%可信区间为0.01~0.05)。结论间苯三酚治疗先兆流产的疗效优于硫酸镁,且不良反应发生率明显降低。
[Abstract]:Effect of system analysis comparison between benzene three phenol and Magnesium Sulfate in the late threatened abortion. Methods to retrieve the China biomedical literature database, Wanfang, CNKI, VIP, indexed by Baidu and other domestic Chinese database published the randomized controlled study and research related to the purpose of offering, using Rev Man 5.3 software combined with analysis of the data which meet the conditions on two groups of drug treatment, onset time, uterine remission time, tocolysis occurred efficiency and adverse reactions of different methods are analyzed and compared. Results the rate of 6 randomized controlled trials were included in the study. The analysis of benzene three phenol compared with the Magnesium Sulfate group, the onset time of the treatment at 0.75 h, 95% confidence interval 0.25~1.24, two the remission time of group contractions showed no significant difference (P=0.5), Magnesium Sulfate compared to benzene three phenol in treatment of threatened abortion rate RR was 1.09 (95% Ci, 1.16 1.03~), adverse reaction The value of RR was 0.02 (95% CI 0.01~0.05). Conclusion benzene three phenol in treatment of threatened abortion is more effective than Magnesium Sulfate, and the incidence of adverse events was reduced.

【作者单位】： 扬州大学临床医学院临床医学系;
【分类号】：R714.21
【正文快照】： 晚期先兆流产指12至27周出现的阴道出血,下腹胀痛,宫口未开未消,胎儿存活。治疗先兆流产的主要原则是利用宫缩抑制剂,抑制宫缩,使胎儿孕龄达到28周以后,提高胎儿的存活率。目前国内的宫缩抑制剂主要有硫酸镁、间苯三酚、盐酸利托君、阿托西班等药物。本文通过收集国内现有的资，

本文编号：1392218