人绒毛膜促性腺激素、甲胎蛋白、非结合雌三醇水平与妊娠期并发症及分娩结局的关系

发布时间：2018-01-16 18:31

本文关键词：人绒毛膜促性腺激素、甲胎蛋白、非结合雌三醇水平与妊娠期并发症及分娩结局的关系　出处：《中国妇幼保健》2016年23期 　论文类型：期刊论文

更多相关文章：妊娠 并发症 β-hCG AFP uE_

【摘要】：目的分析血清人绒毛膜促性腺激素(β-hCG)、甲胎蛋白(AFP)、非结合雌三醇(uE_3)水平与妊娠期并发症及分娩结局的关系。方法以2014年3月-2015年3月在该院进行产前检查,孕中期进行血清β-hCG、AFP、uE_3水平检测,并在该院住院分娩的产妇为观察对象,根据血清β-hCG、AFP、uE_3的MoM值分为正常组、过高组和降低组。比较β-hCG、AFP、uE_3正常组、升高组和降低组妊娠并发症和不良分娩结局的发生率。结果血清AFP水平过高组发生妊娠期高血压、妊娠期糖尿病和胎盘早剥以及早产的例数明显多于正常组,差别具有统计学意义(P0.05);血清β-hCG过高组和uE_3降低组产妇发生妊娠期高血压、妊娠期糖尿病和胎盘早剥的例数明显多于正常组,且早产和产后出血的发生率也较正常组高,差异有统计学意义(P0.05)。结论高水平的β-hCG、AFP和低水平的uE_3与妊娠期并发症和不良分娩结局的发生密切相关。
[Abstract]:Objective to analyze serum human chorionic gonadotropin (尾 -hCGN). The relationship between the level of unconjugated estriol uE _ 3 and the complications of pregnancy and the outcome of delivery. Methods Prenatal examination was conducted in the hospital from March 2014 to March 2015. The serum levels of 尾 -hCGCG-AFPnuE3 were measured in the second trimester of pregnancy, and the pregnant women who were delivered in the hospital were observed according to the serum levels of 尾 -hCGCG-AFP. The MoM values of uE_3 were divided into normal group, hypertrophic group and decreased group. Results the incidence of pregnancy complications and poor delivery outcome in the high serum AFP group was significantly higher than that in the control group. Results the hypertension complicating pregnancy was found in the high serum AFP level group. The number of cases of gestational diabetes mellitus, placental abruption and preterm delivery was significantly higher than that of normal group, and the difference was statistically significant (P 0.05). Hypertension complicating pregnancy, gestational diabetes mellitus and placental abruption were more common in the high serum 尾 -hCG group and uE_3 reduction group than in the normal group, and the incidence of premature delivery and postpartum hemorrhage was also higher than that in the normal group. Conclusion the high level of 尾 -hCGN AFP and the low level of uE_3 are closely related to the occurrence of pregnancy complications and poor delivery outcome.
【作者单位】：南京市妇幼保健院;
【分类号】：R714.2
【正文快照】： 妊娠期由于特殊的生理性改变,血容量的增加、体内雌孕激素分泌的增加、生长抑素等拮抗胰岛素受体的激素分泌的增高,均可促进妊娠期高血压、妊娠期糖尿病以及妊娠期合并心脏病的发生,增加早产、引产以及剖宫产的几率,并可导致4%~5%左右的胎儿宫内生长发育窘迫和新生儿缺血缺氧

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