妊娠合并宫颈癌9例临床分析

发布时间：2018-01-18 10:27

  本文关键词：妊娠合并宫颈癌9例临床分析　出处：《浙江大学》2014年硕士论文　论文类型：学位论文

  更多相关文章： 妊娠 宫颈癌 临床表现 诊断 治疗

【摘要】：目的：分析妊娠合并宫颈癌的临床特点、诊断和治疗。 方法：回顾性分析自2000年1月至2014年1月我院收治的10例妊娠合并宫颈癌患者,其中1例诊断明确后即行剖宫产术,术后自动出院,另9例均接受不同治疗,总结分析其临床特点、诊断及治疗方法。 结果：入选9例患者年龄23～42岁,平均年龄33.1岁。平均孕周18周,早孕5例(5/9),中孕2例(2/9),晚孕2例(2/9)。其中4例因发现宫颈异常入院,3例因阴道不规则流血入院,2例因阴道接触性出血入院。9例患者均经病理检查诊断,主要病理类型为宫颈鳞癌(8/9),4例Ib1期,4例Ib2期,另1例为宫颈腺鳞癌Ib1期。妊娠合并宫颈鳞癌患者年龄、临床分期、细胞分化、肿瘤大小和宫颈深肌层浸润与非妊娠合并宫颈鳞癌之间差异非常显著。宫颈鳞癌患者中4例肿瘤直径4cm,4例肿瘤直径≥4cm。4例孕早期患者选择放弃胎儿直接接受规范化治疗,行宫颈癌改良根治术。4例孕中、晚期患者行子宫下段剖宫产术,其中1例剖宫产术后行化疗,2例剖宫产术后行新辅助化疗,再行宫颈癌改良根治术,1例剖宫产术后直接行宫颈癌改良根治术,术后建议放疗。1例孕早期患者行宫颈癌改良根治术后续化疗。孕中期患者2例中1例新生儿经抢救存活,1例放弃；孕晚期2例新生儿均存活。 结论：妊娠合并宫颈鳞癌患者年龄、临床分期、肿瘤大小和深肌层浸润与非妊娠合并宫颈鳞癌之间差异非常显著；妊娠合并宫颈癌多为早期患者,治疗应个体化,对于中、晚孕期发现的宫颈癌可根据患者肿瘤分期、孕周、患者意愿等情况延迟治疗至胎儿成熟。
[Abstract]:Objective: to analyze the clinical features, diagnosis and treatment of cervical cancer in pregnancy. Methods: from January 2000 to January 2014, 10 cases of pregnancy complicated with cervical cancer in our hospital were analyzed retrospectively. One case underwent cesarean section immediately after diagnosis, and was discharged automatically after operation. The other 9 cases were treated with different treatment, their clinical characteristics, diagnosis and treatment were summarized and analyzed. Results: the age of 9 patients was 2342 years old, with an average age of 33.1 years, an average gestational age of 18 weeks, an early pregnancy of 5 / 9, and a middle pregnancy of 2 / 9). Among them, 4 cases were admitted to hospital because of abnormal cervix. 3 cases were admitted to hospital because of irregular bleeding of vagina, 2 cases were admitted to hospital because of vaginal contact hemorrhage, 9 cases were diagnosed by pathological examination. The main pathological types were 4 cases of Ib1 stage 4 cases of Ib2 stage and 1 case of Ib1 stage of cervical adenosquamous carcinoma. Age, clinical stage and cell differentiation of pregnancy complicated with cervical squamous cell carcinoma were the main pathological types. There was a significant difference between the size of the tumor and the infiltration of the deep myometrium of the cervix and non-pregnant women with cervical squamous cell carcinoma. The diameter of the tumor was 4cm in 4 patients with cervical squamous cell carcinoma. 4 cases with tumor diameter 鈮，

本文编号：1440557