不孕症患者卵巢血流灌注预测卵泡发育的三维超声研究

发布时间：2018-01-20 02:01

本文关键词： 不孕症三维能量多普勒卵巢血流　出处：《广东医学》2017年21期 　论文类型：期刊论文

【摘要】：目的探讨卵巢血流灌注预测卵泡发育的可行性。方法收集不孕症患者48例,在卵泡期行经阴道三维超声检查,计算双侧卵巢窦卵泡个数并记录双侧卵巢三维能量多普勒图像,运用4Dview软件脱机分析双侧卵巢体积、卵巢血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)。所有卵巢参数按监测排卵结果分成有成熟卵泡组及无成熟卵泡组,比较两组间上述参数的差异性并进行ROC曲线分析。结果两组卵巢VI、FI及VFI比较差异有统计学意义(P0.05),窦卵泡数及卵巢体积两组间差异无统计学意义,VI、FI、VFI、窦卵泡数及卵巢体积对应的ROC曲线下面积分别为0.805、0.833、0.838、0.577、0.578,以约登指数寻找的VI、FI、VFI界值分别为3.25、27.97、0.87,但敏感度与特异度不高。结论卵巢血流对卵泡发育有明确意义,卵泡期卵巢血流VI、FI、VFI对卵泡发育有一定的预测性,但最佳界值的敏感度及特异度不高。窦卵泡数及卵巢体积对卵泡发育无明显预测价值。
[Abstract]:Objective to investigate the feasibility of ovarian perfusion in predicting follicle development. Methods 48 patients with infertility were examined by transvaginal three dimensional ultrasound in follicular phase. The number of ovarian antral follicles was calculated and three dimensional power Doppler images were recorded. The ovarian volume, ovarian vascularization index (VIV) and blood flow index (FI) were analyzed offline by 4Dview software. Vascularized blood flow index (VFI). All ovarian parameters were divided into mature follicle group and non-mature follicle group according to the results of ovulation monitoring. The differences of the above parameters between the two groups were compared and the ROC curves were analyzed. Results the difference of VIFI and VFI between the two groups was statistically significant (P 0.05). There was no significant difference in the number of antral follicles and the volume of ovaries between the two groups. The area under the ROC curve of the number of antral follicles and the volume of ovaries was 0.805 卤0.833, respectively. The values of VFI and VFI were found to be 3.25 ~ 27.97 ~ 0.87 by using the Yorden index, respectively, and 0.838 ~ (0.57) ~ 0.57 ~ (7) ~ (th) ~ (0.57) ~ (th) ~ (th) ~ (th), respectively. But the sensitivity and specificity are not high. Conclusion the ovarian blood flow has a clear significance in follicular development, and the ovarian blood flow in follicular phase VIFI has a certain predictive effect on follicular development. However, the sensitivity and specificity of the best cutoff value were not high. The number of antral follicles and the volume of ovaries had no significant predictive value for follicular development.
【作者单位】：广州中医药大学第一附属医院超声科;广州中医药大学研究生院;
【基金】：广东省中医药管理局课题(编号:20161128)
【分类号】：R445.1;R711.6
【正文快照】： 成熟卵泡发育是成功妊娠的关键,卵巢血流灌注对卵泡发育有重要作用。大量研究探讨了卵巢体积、卵巢血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)对预测卵巢储备功能及妊娠结局的预测价值,但尚无一致的定论。笔者在临床工作中发现,不孕症患者双侧卵巢在窦卵泡数、体积、

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