激光辅助孵化胚胎透明带内层方法的临床价值

发布时间：2018-01-22 00:43

本文关键词： 激光辅助孵化 IVF-ET 透明带　出处：《现代妇产科进展》2017年11期 　论文类型：期刊论文

【摘要】：目的:评估采用新鲜第3天胚胎透明带内层消融与外层消融对反复种植失败患者妊娠结局的影响。方法:将151例反复种植失败的患者分为3组:透明带打通组(52例)进行激光辅助孵化将胚胎透明带打通;透明带外层消融组(49例)进行激光辅助孵化以消融胚胎透明带的外层;透明带内层消融组(50例)进行激光辅助孵化以消融胚胎透明带的内层。比较3组的临床妊娠率、多胎率和种植率。结果:透明带内层消融组的临床妊娠率、种植率和多胎妊娠率均高于透明带外层消融组,差异有统计学意义(P0.05);透明带内层消融组的临床妊娠率、种植率、多胎妊娠率略高于透明带打通组,但差异无统计学意义。结论:进行激光辅助孵化以消融胚胎透明带内层,显著提高了反复种植失败患者的妊娠率和种植率。
[Abstract]:Objective: to evaluate the effect of inner and outer ablation of the pellucida zone on the third day of embryo implantation on pregnancy outcome in patients with repeated implantation failure. Methods: 151 patients with failed implantation were divided into 3 groups. Transparent banding group (. 52 cases were treated with laser assisted hatching to open the pellucida; The outer layer of embryo pellucida was ablated by laser assisted incubation. The clinical pregnancy rate, multiple pregnancy rate and implantation rate were compared among the three groups. Results: the clinical pregnancy rate of the inner pellucida ablation group was compared with that of the inner pellucida ablation group. The implantation rate and pregnancy rate of multiple pregnancy were higher than those of the outer pellucida ablation group, and the difference was statistically significant (P 0.05). The clinical pregnancy rate, implantation rate and multiple pregnancy rate in the pellucida inner layer ablation group were slightly higher than those in the pellucida band opening group, but the difference was not statistically significant. Conclusion: laser assisted incubation is performed to melt the inner pellucida zone of embryo. The pregnancy rate and implantation rate were significantly increased in patients with repeated failed implantation.
【作者单位】：海口玛丽医院生殖中心;
【基金】：海南省卫生厅基金资助项目(No:1601320319A2001)
【分类号】：R714.8
【正文快照】： 辅助孵化(AH)已证实有效增加种植率和妊娠率,特别是对高龄[1-2]、多囊卵巢综合征[3]、复发性植入失败及冷冻复苏胚胎的患者[4-5]。AH方法包括机械部分剥离、化学钻孔和激光技术。激光辅助孵化(LAH)比其他AH技术更有利于胚胎[6],是一种安全快速的方法[7-8]。人类胚胎的透明带是

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