宫颈分泌物与盆腔液解脲支原体与沙眼衣原体检测在输卵管性不孕患者感染评估中的应用

发布时间：2018-01-22 21:02

本文关键词： 宫颈分泌物盆腔液输卵管性不孕解脲支原体沙眼衣原体感染　出处：《中华医院感染学杂志》2017年22期 　论文类型：期刊论文

【摘要】：目的研究探讨宫颈分泌物与盆腔液解脲支原体(Uu)、沙眼衣原体(Ct)检测在输卵管性不孕患者感染评估中的应用价值。方法选取2015年7月-2016年9月于医院检测的输卵管性不孕患者72例,设置为试验组;另抽取同期来院体检的健康人员31名作为参考组,实施聚合酶链反应(PCR)法检测宫颈分泌物与盆腔液内Uu、Ct,分析患者感染率。结果试验组患者宫颈分泌物中Uu、Ct检出率分别为30.56%、5.56%,显著高于对照组的9.68%、0.00%,试验组患者盆腔液中Uu检出率为4.17%,显著高于对照组的0.00%(P0.05);继发性输卵管性不孕患者宫颈分泌物中Uu、Ct检出率显著高于原发性输卵管性不孕者,继发性输卵管性不孕患者盆腔液中Uu检出率显著高于原发性输卵管性不孕者(P0.05);经药敏检测,Uu对强力霉素的敏感率为100.00%、交沙霉素的敏感率为96.00%,对四环素、红霉素敏感率最低。结论输卵管性不孕患者与Uu、Ct感染有着密切关联性,建议加强Uu、Ct检测,对Uu、Ct感染者可采取药敏试验,选择合理的抗菌药物治疗,抑制Uu、Ct对输卵管的持续性损害。
[Abstract]:Objective to study the Ureaplasma Urealyticum Ureaplasma Urealyticum (UU) in cervical secretion and pelvic fluid. The value of Chlamydia trachomatis (Chlamydia trachomatis) in the evaluation of infection in patients with tubal infertility methods 72 patients with tubal infertility were selected from July 2015 to September 2016. Set up as the test group; In addition, 31 healthy persons were selected as reference group and detected by polymerase chain reaction (PCR) for UuCt in cervical secretion and pelvic fluid. Results the positive rate of UU Ct in cervical secretion of patients in the test group was 30.56% and 5.56% respectively, which was significantly higher than that in the control group (9.68%). The detection rate of UU in pelvic fluid in the test group was 4.17, which was significantly higher than that in the control group. The detection rate of UU Ct in cervical secretion of secondary tubal infertility was significantly higher than that in primary tubal infertility. The positive rate of UU in pelvic fluid of secondary tubal infertility was significantly higher than that in primary tubal infertility (P 0.05). The sensitivity of Uu to doxycycline was 100.00g, the sensitivity rate of josamycin was 96.00, the sensitivity to tetracycline and erythromycin was the lowest. Ct infection is closely related. It is suggested that the detection of UUU Ct should be strengthened, and the drug sensitivity test should be taken for the patients infected with Ct, and rational antimicrobial therapy should be selected to inhibit UU. Ct sustained damage to fallopian tubes.
【作者单位】：山东济宁医学院附属医院生殖医学科;山东烟台毓璜顶医院生殖医学科;
【基金】：山东省自然科学基金资助项目(ZR2010HM040)
【分类号】：R711.6
【正文快照】： 病理因素的复杂性与不确定性,造成致病原因不明,由此也受到医疗领域学者重视[1]。Gregorczyk[2]通过病因探析报道,不孕症诸多病发诱因中当属生殖道病原体感染具高威胁,当前全球约9 000万夫妻受到不孕症困扰造成无法育养子女,而这类患者中约37%~56%属于治疗不及时或未得到治疗

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