促排卵后分别接受戊酸雌二醇、芬吗通雌二醇治疗的不孕症患者子宫内膜容受性观察

发布时间：2018-01-26 12:30

  本文关键词： 不孕症 克罗米芬 戊酸雌二醇 芬吗通雌二醇 子宫内膜容受性　出处：《山东医药》2015年28期 　论文类型：期刊论文

【摘要】：目的观察克罗米芬(CC)促排卵后分别接受戊酸雌二醇(补佳乐)、芬吗通雌二醇治疗的不孕症患者子宫内膜容受性。方法选择CC促排卵后子宫内膜变薄的不孕症患者120例,随机分为三组,均于月经第8天开始补充外源性雌激素,A组补佳乐口服及阴道用药,B组口服补佳乐,C组芬吗通雌二醇片口服及阴道用药;分别于用药3 d后及人绒毛膜促性腺激素(HCG)日下午行阴道超声检查,比较三组子宫内膜厚度、类型、容积及内膜下血流情况,并随访临床妊娠率。结果补充雌激素3 d后,A、B、C组子宫内膜厚度分别为(6.57±1.21)、(7.00±1.11)、(7.74±1.37)mm,HCG日分别为(8.08±2.12)、(8.70±2.17)、(9.96±2.38)mm,C组B组A组(P均0.05)。补充雌激素3 d后,A、B、C组子宫内膜容积≥2 m L分别为15、18、25例,HCG日分别为20、22、31例,C组均多于A、B组(P均0.05);三组子宫内膜类型、内膜下血流比较均无统计学差异(P均0.05)。A、B、C组临床妊娠率分别为17.5%、20.0%、25.0%,组间比较,P均0.05。结论与补佳乐比较,芬吗通雌二醇片可明显改善CC促排卵后子宫内膜变薄的不孕症患者内膜厚度及容积,但在子宫内膜类型、子宫内膜下血流及临床妊娠率方面比较无统计学差异。
[Abstract]:Objective to observe the effect of estradiol valerate on ovulation induced by clomiphene. Methods 120 infertile patients with infertility treated with fentone estradiol were randomly divided into three groups. On the 8th day of menstruation, oral administration of Bujialao in group A of exogenous estrogen and oral administration of Fenmatone estradiol in group B and oral administration of fentone estradiol in group B were performed. The thickness, type, volume and subendometrial blood flow of the three groups were examined by vaginal ultrasound 3 days after treatment and on the afternoon of human chorionic gonadotropin (HCG). Results the endometrial thickness was 6.57 卤1.21 in group C after estrogen supplementation for 3 days, and 7.00 卤1.11 in group A (P < 0.05). The HCG days of 7.74 卤1.37 mm / d were 8.08 卤2.12 卤8.70 卤2.17 卤9.96 卤2.38 mm respectively. The endometrial volume 鈮，

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