腹腔镜和开腹在早期卵巢癌全面分期手术中疗效的Meta分析

发布时间：2018-01-27 01:03

本文关键词： 卵巢肿瘤腹腔镜外科手术剖腹术治疗结果 Meta分析　出处：《中国全科医学》2015年02期 　论文类型：期刊论文

【摘要】：目的比较腹腔镜(LPS)与开腹(LPT)在早期卵巢癌全面分期手术中的疗效。方法计算机检索Pub Med、EMBase、Cochrane Library、万方数据库、中国生物医学文献数据库、中国知网1990-01-01至2014-02-12有关LPS和LPT在早期卵巢癌全面分期手术中疗效的文献。采用Rev Man 5.2.9软件对手术时间、术中失血量、淋巴结切除数、术中肿瘤破裂发生率、术后肛门排气时间、手术并发症发生率、术后疼痛评分(VAS)、术后住院时间、术后复发率和术后病死率进行分析。结果共纳入18篇临床对照研究(CCT)文献,包括434例LPS患者和788例LPT患者,文献质量较好。LPS组较LPT组术中失血量少〔MD=-207.86,95%CI(-285.87,-129.86),P0.05〕,术后肛门排气时间早〔MD=-25.26,95%CI(-31.07,-19.45),P0.05〕,手术并发症发生率低〔OR=0.30,95%CI(0.20,0.45),P0.05〕,术后疼痛轻〔MD=-2.84,95%CI(-4.39,-1.29),P0.05〕,住院时间短〔MD=-4.14,95%CI(-4.63,-3.66),P0.05〕,而两组手术时间、淋巴结切除数、术中肿瘤破裂率、术后复发率、病死率间差异无统计学意义(P0.05)。结论 LPS下早期卵巢癌全面分期手术创伤小、恢复快,远期效果与LPT手术相比无明显差异。
[Abstract]:Objective to compare the efficacy of laparoscopic LPS (LPS) and laparotomy (LPT) in the early stage operation of ovarian cancer. Cochrane Library, Wanfang Database, Chinese Biomedical Literature Database. Literature from January 1990 to January 12, 2014-02-12 on the efficacy of LPS and LPT in the treatment of early ovarian cancer by comprehensive staging. Rev Man was used. 5.2.9 Software versus operation time. Blood loss, lymph node excision, tumor rupture, postoperative anal exhaust time, postoperative complications, postoperative pain score, postoperative hospitalization time. The recurrence rate and postoperative mortality were analyzed. Results 18 clinical controlled studies including 434 patients with LPS and 788 patients with LPT were included. The volume of blood loss in the LPS group was lower than that in the LPT group, and the blood loss in the LPS group was less than that in the LPT group (P 0.05). The postoperative anus exhaust time was earlier than that of MD-25.2695. CI-31.07- 19.45% P0.05. the incidence of postoperative complications was 0.30. After operation, the pain was mild (MD-2.84). The pain was 4.39 ~ (-1.29) (P _ (0.05)) (P _ (0.05), P _ (0.05), P _ (0.05)) in the group of 0.20 ~ 0.45 ~ 0.45 ~ 0.45 ~ 0.20 ~ 0.45. The time of operation, the number of lymphadenectomy, the rate of tumor rupture during operation and the recurrence rate after operation in the two groups were shorter than that in the control group. Conclusion the overall stage operation of early ovarian cancer in LPS has less trauma and faster recovery, and there is no significant difference in long-term effect compared with LPT operation.
【作者单位】：承德医学院附属医院妇科;承德市丰宁满族自治县医院妇产科;承德医学院附属医院肝胆外科;承德医学院预防医学教研室;
【基金】：河北省承德市科学技术研究与发展计划(20123122)
【分类号】：R737.31
【正文快照】： Laparoscopic and Laparotomy in Staging Operation of Early-stage Ovarian Cancer:A Meta-analysis ZHAO Lu-wen,SONG Xiao-li,YU Ai-jun,et al.Department of Gynecology,the Affiliated Hospital of Chengde Medical College,Chengde 067000,China卵巢癌是女性常见恶性肿

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