探讨硫酸镁与硝苯地平治疗妊高症的疗效

发布时间：2018-01-29 09:14

本文关键词： 妊高症硫酸镁硝苯地平疗效　出处：《临床医药文献电子杂志》2016年44期 　论文类型：期刊论文

【摘要】：目的探讨硫酸镁与硝苯地平治疗妊高症的疗效。方法选取我院2015年9月~2016年9月妇产科收治的妊高症患者130例作为研究对象,随机分为对照组和观察组,对照组单用硫酸镁治疗,观察组采用硫酸镁与硝苯地平治疗,比较两组患者的疗效、血压及24 h尿蛋白定量、脐动脉阻力指数、红细胞比容、血粘度。结果观察组和对照组治疗有效率分别为为95.38%和81.54%,两组患者治疗效比较,观察组明显较高于对照组,差异有统计学意义(P0.05);治疗后观察组的收缩压、舒张压及24 h尿蛋白定量监测结果均明显较对照组改善,差异有统计学意义(P0.05);治疗后观察组的脐动脉阻力指数、红细胞比容、血粘度等指标均明显优于对照组,差异有统计学意义(P0.05)。结论硫酸镁与硝苯地平治疗妊高症有确切疗效,控制血压效果强,能有效改善妊娠结局,提高胎儿质量。
[Abstract]:Objective to investigate the efficacy of magnesium sulfate and nifedipine in the treatment of pregnancy induced hypertension (PIH). Control group and observation group were randomly divided into control group and observation group. The control group was treated with magnesium sulfate and nifedipine. The curative effect, blood pressure, 24 h urine protein and umbilical artery resistance index were compared between the two groups. Results the effective rates of the observation group and the control group were 95.38% and 81.54, respectively. The curative effect of the observation group was significantly higher than that of the control group. The difference was statistically significant (P 0.05). The results of systolic blood pressure, diastolic blood pressure and 24 h urine protein quantitative monitoring in the observation group were significantly better than those in the control group (P 0.05). After treatment, the indexes of umbilical artery resistance index, erythrocyte volume and blood viscosity in the observation group were significantly better than those in the control group. Conclusion magnesium sulfate and nifedipine are effective in the treatment of pregnancy induced hypertension and can effectively improve pregnancy outcome and fetal quality.
【作者单位】：湖北省襄阳市第三人民医院妇产科;
【分类号】：R714.246
【正文快照】： 妊高症是妊娠期常见疾病,临床表现为血压明显升高,伴有蛋白尿、水肿等,严重时可引起多系统的功能紊乱,继发昏迷、全身肌肉痉挛,甚至发生产妇心力衰竭及肾衰竭,胎儿发生早产或死亡,严重威胁母婴生命安全[1]。因此,临床对妊高症的治疗十分重视。本病的发病机制尚未明确,临床缺乏

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