子痫前期孕妇胎儿肺成熟度的超声观察

发布时间：2018-02-12 20:42

本文关键词： 胎肺成熟度超声子痫前期肺头比新生儿呼吸窘迫综合征　出处：《中国医科大学学报》2017年04期 　论文类型：期刊论文

【摘要】：目的通过对比观察正常孕妇和子痫前期(PE)孕妇胎儿肺结构的超声特点,探讨PE对胎肺成熟度(FLM)的影响。方法选取早发型(29~34周)PE患者140例,晚发型(34~39周)PE患者100例,同时纳入同孕龄孕妇240例作为对照组,观察2组患者FLM的超声测量参数,随访产后新生儿呼吸窘迫综合征(NRDS)的发生情况,对比分析PE对FLM的影响。结果早发型PE组胎儿右肺面积小于同孕龄正常组胎儿,差异有统计学意义;晚发型PE组与同孕龄正常组胎儿比较无差异。早发型和晚发型PE组肺头比(LHR)与同孕龄正常组胎儿比较无差异。早发型和晚发型PE组主肺动脉收缩期加速时间/射血时间(AT/ET)高于同孕龄正常组胎儿,差异有统计学意义。各型PE组与同孕龄胎儿产后发生NRDS情况比较无差异。结论 PE对胎儿肺组织功能成熟无明显影响,在肺组织结构成熟方面可能先于同孕龄无PE胎儿。
[Abstract]:Objective to investigate the effects of PE on fetal lung maturity (FLM) in normal and preeclampsia (PEP) pregnant women. Methods 140 cases of PE with early onset and 34 weeks with PE and 100 cases with PE with late onset were studied. At the same time, 240 pregnant women of the same gestational age were included as the control group. The ultrasonic parameters of FLM were observed and the incidence of neonatal respiratory distress syndrome (NRDS) was followed up. Results the area of right lung of early onset PE fetus was smaller than that of normal fetus of the same gestational age, and the difference was statistically significant. There was no difference between the late type PE group and the normal fetus of the same gestational age, but there was no difference between the early type PE group and the late type PE group in the lung head ratio LHR.There was no difference between the late type PE group and the same gestational age group. The blood time of AT-ETs was higher than that of normal fetuses of the same gestational age. There was no significant difference in postpartum NRDS between different PE groups and the same gestational age fetuses. Conclusion PE has no significant effect on fetal lung tissue maturation and may be prior to the same gestational age without PE fetus in lung tissue structure maturation.
【作者单位】：河北省唐山市妇幼保健院功能科;河北省唐山市妇幼保健院产二科;
【基金】：河北省2016年度医学科学研究重点课题(20160840)
【分类号】：R445.1;R714.5

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