四君子汤合黄芪辅助饮食运动疗法治疗妊娠糖尿病气阴两虚证

发布时间：2018-02-15 15:44

本文关键词： 四君子汤妊娠糖尿病气阴两虚疗效　出处：《中国实验方剂学杂志》2015年21期 　论文类型：期刊论文

【摘要】：目的:探讨四君子汤合黄芪辅助饮食运动疗法治疗妊娠糖尿病气阴两虚证临床效果。方法:研究对象选取本院近年来收治妊娠糖尿病气阴两虚证患者240例,采用随机数字表法分为对照组和中医组,每组各120例;其中对照组患者采用常规饮食运动疗法治疗,中医组患者则在此基础上加用四君子汤合黄芪辅助治疗;比较两组患者临床疗效、治疗前后血糖、血脂及肾脏功能指标水平,妊娠结局等。结果:对照组和中医组患者治疗总有效率分别为78.33%,91.67%;中医组患者临床疗效显著优于对照组,差异有统计学意义(P0.05);对照组患者治疗后空腹血糖(FPG),餐后2 h血糖(2 h PG)及糖化血红蛋白(Hb A1c)指标分别为(9.77±1.03)mmol·L-1,(11.30±1.64)mmol·L-1,(9.84±1.10)%;中医组患者治疗后FPG,2 h PG及Hb A1c指标分别为(5.48±0.62)mmol·L-1,(8.62±1.27)mmol·L-1,(7.03±0.64)%;中医组患者治疗后血糖、血脂及肾脏功能指标水平均显著优于对照组治疗后,差异有统计学意义(P0.05);中医组患者早产、子痫前期、羊水过多、新生儿窘迫征及新生儿高胆红素血症发生率均显著低于对照组,差异有统计学意义(P0.05);两组患者剖宫产和妊娠期高血压发生率比较差异无统计学意义。结论:四君子汤合黄芪辅助饮食运动疗法治疗妊娠糖尿病气阴两虚证可有效缓解糖尿病症状,控制血糖和血脂水平,改善肾脏功能,并对妊娠结局具有积极影响。
[Abstract]:Objective: to investigate the clinical effect of Sijunzi decoction combined with Astragalus membranaceus supplementary diet and exercise therapy in treating qi and yin deficiency syndrome in pregnancy diabetes mellitus. Methods: 240 cases of pregnancy diabetes mellitus with deficiency of qi and yin were treated in our hospital in recent years. The patients in the control group were treated with routine diet and exercise therapy, and the patients in the TCM group were treated with Sijunzi decoction combined with Astragalus membranaceus. Results: the total effective rate of the control group and TCM group was 78.33 and 91.67 respectively, and the clinical efficacy of TCM group was significantly better than that of the control group. There were significant differences in fasting blood glucose (FPGG), 2 h postprandial blood glucose (PGN) and HbA1c (9.77 卤1.03mmol 路L-1) and 9.84 卤1.64mmol 路L-1 (9.84 卤1.1084 卤1.1084 卤1.1084 mmol 路L ~ (-1)) in the control group, and 5.48 卤0.62 卤0.62 卤1.27 mmol 路L ~ (-1) mg 路L ~ (-1) and 7.64 卤0.64 mmol 路L ~ (-1) respectively in the two hours of treatment in the Chinese medicine group, and 5.48 卤0.62 卤0.62 卤1.27 mmol 路L ~ (-1) mmol 路L ~ (-1) and 7.03 卤0.64 mmol 路L ~ (-1) of blood glucose in the Chinese medicine group, respectively. The levels of blood lipids and renal function were significantly better than those of the control group (P 0.05), and the patients in TCM group were preterm labor, preeclampsia, amniotic fluid, amniotic fluid. The incidence of neonatal distress and neonatal hyperbilirubinemia were significantly lower than those in the control group. There was no significant difference in the incidence of cesarean section and hypertension complicating pregnancy between the two groups. Conclusion: Sijunzi decoction combined with Huangqi diet and exercise therapy can be effective in the treatment of deficiency of qi and yin in gestational diabetes mellitus. To relieve the symptoms of diabetes, Control of blood glucose and blood lipid levels, improve renal function, and have a positive impact on pregnancy outcomes.
【作者单位】：青海红十字医院;
【基金】：青海省科技厅应用基础研究计划项目(2015-ZJ-765)
【分类号】：R714.256

【参考文献】