多毛和非多毛多囊卵巢综合征三维能量多普勒超声及内分泌指标特征

发布时间：2018-02-16 01:09

本文关键词： 多囊卵巢综合征多毛症超声检查内分泌学　出处：《中国超声医学杂志》2015年01期 　论文类型：期刊论文

【摘要】：目的比较不同临床表现的多囊卵巢综合征患者三维能量多普勒超声参数与内分泌指标特征。方法将PCOS患者分为多毛PCOS组(HI-PCOS组)39例和非多毛PCOS组(NHI-PCOS组)46例。比较两组卵巢体积、间质体积和卵泡体积。比较两组卵巢血流量化指标:血管化指数(VI),血流指数(FI),血管化-血流指数(VFI)。比较两组黄体生成素(LH),卵泡刺激素(FSH),孕酮(P),雌二醇(E2),总睾酮(T),泌乳素(PRL),性激素结合球蛋白(SHBG),游离睾酮指数(FTI),血糖(FPG),血浆胰岛素(FINS),稳态模型指数(HOMA-IR)。分析超声参数和内分泌指标的相关性。结果 HI-PCOS组患者间质体积、VI和VFI、LH、T、FTI、FPG、FINS、HOMA-IR较NHI-PCOS组增大,差异有统计学意义(P0.05、0.01)。HI-PCOS组患者SHBG较NHI-PCOS组降低,差异有统计学意义(P0.01)。HI-PCOS组中,间质体积与HOMA-IR、FTI呈正相关(r=0.324、0.912,P0.05、0.01)。VI、VFI与FTI呈正相关(r=0.472、0.556,P0.05)。结论多毛和非多毛PCOS患者有不同的超声参数和内分泌指标特征。
[Abstract]:Objective to compare the three dimensional power Doppler ultrasound parameters and endocrine parameters of patients with polycystic ovary syndrome (PCOS) with different clinical manifestations. Methods PCOS patients were divided into three groups: 39 cases of HI-PCOS and 46 cases of non-hairy PCOS. Interstitial volume and follicular volume were compared between the two groups: vascularization index (VII), blood flow index (FI), vascularization index (VFI), vascularization index (VFI), luteinizing hormone (LHH), follicle stimulating hormone (FSH), progesterone (P), estradiol, estradiol (E _ 2), total testosterone (T). Prolactin prolactin (PRL), sex hormone binding globulin (SHBG), free testosterone index (FTI), blood glucose (FPG), plasma insulin, homeostasis model index (HOMA-IRN). The correlation between ultrasonic parameters and endocrine parameters was analyzed. Results the interstitial volume of HI-PCOS patients was significantly higher than that of NHI-PCOS group. There was a significant difference in SHBG between HI-PCOS group and NHI-PCOS group. In HI-PCOS group, there was a positive correlation between interstitial volume and HOMA-IRFTI. VIVFI was positively correlated with FTI. Conclusion there are different ultrasonic parameters and endocrine parameters in patients with hirsutism and non-hairy PCOS.
【作者单位】：复旦大学附属妇产科医院超声科;复旦大学附属妇产科医院中西医结合妇科;
【基金】：上海市卫生局青年科研项目(No.20114Y180)
【分类号】：R711.75;R445.1

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