CA125与CA19-9检测在妇科肿瘤诊断中的作用

发布时间：2018-02-20 00:33

本文关键词： 妇科肿瘤肿瘤抗原肿瘤抗原- 卵巢癌子宫内膜癌　出处：《慢性病学杂志》2016年11期 　论文类型：期刊论文

【摘要】：目的探讨肿瘤抗原125(CA125)与肿瘤抗原19-9(CA19-9)检测对妇科肿瘤诊断的价值。方法收集来福建省立金山医院就诊的经病理组织学确诊为妇科肿瘤的患者96例,其中良性组21例、恶性组75例;同时选取42例健康体检的健康女性作为对照组。分别检测血清CA125与CA19-9水平,然后对恶性组、良性组和对照组进行比较,并对不同恶性肿瘤患者血清CA125及CA19-9阳性率进行分析。结果恶性组的CA125及CA19-9水平均高于对照组和良性组,良性组的CA125及CA19-9水平均高于对照组,差异均有统计学意义(P0.05);卵巢癌和子宫内膜癌患者的CA125阳性表达率高于宫颈癌组,差异有统计学意义(P0.05);CA125和CA19-9联合检测对妇科肿瘤诊断的准确性高于单独检测CA125或CA19-9。结论 CA125、CA19-9的检测有助于妇科肿瘤的诊断和鉴别诊断,联合检测的诊断价值更高。
[Abstract]:Objective to investigate the value of tumor antigen 125 (CA125) and tumor antigen 19-9 (CA19-9) in the diagnosis of gynecological tumors. Methods 96 cases of gynecologic tumors diagnosed by histopathology were collected from Jinshan Hospital of Fujian Province, including 21 cases of benign group and 75 cases of malignant group. At the same time, 42 healthy women were selected as control group. The serum levels of CA125 and CA19-9 were measured, and then the malignant group, benign group and control group were compared. Results the levels of CA125 and CA19-9 in malignant group were higher than those in control group and benign group, and the levels of CA125 and CA19-9 in benign group were higher than those in control group. The positive expression rate of CA125 in ovarian cancer and endometrial carcinoma was higher than that in cervical cancer. The accuracy of combined detection of CA125 and CA19-9 in gynecological tumors was higher than that in CA125 or CA19-9.Conclusion the detection of CA125 and CA19-9 is helpful to the diagnosis and differential diagnosis of gynecologic tumors, and the diagnostic value of combined detection is higher.
【作者单位】：福建医科大学省立临床医学院福建省立金山医院妇产科;
【分类号】：R737.3

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