凝血功能检测在妊娠期糖尿病孕妇中的意义

发布时间：2018-02-24 12:24

本文关键词： 孕妇糖尿病血栓弹力图血小板凝血象　出处：《重庆医学》2016年09期 　论文类型：期刊论文

【摘要】：目的比较妊娠期糖尿病(GDM)患者与健康孕妇实验室凝血指标和血栓弹力图(TEG)参数的差异。方法回顾分析2013年6月至2014年7月在重庆医科大学附属第二医院产科住院的GDM患者46例,健康孕妇49例,比较其血栓弹力图、血图及凝血检测结果。结果 GDM组和对照组的传统凝血项目比较,国际标准化比值、凝血酶原时间差异具有统计学意义(P0.05),而活化部分凝血活酶时间、纤维蛋白原、血小板计数差异无统计学意义(P0.05),GDM组和对照组的TEG常用指标比较,发现R、K、Angle角、MA、CI值差异均有统计学意义(P0.05)。结论 TEG较传统凝血功能检查监测GDM患者的血栓前状态的进展更敏感,对指导临床早期干预、缓解或延迟并发症,改善母婴结局具有一定意义。
[Abstract]:Objective to compare the differences of laboratory coagulation parameters and thromboelastography parameters between patients with gestational diabetes mellitus (GDM) and healthy pregnant women. Methods 46 GDM patients hospitalized in the second affiliated Hospital of Chongqing Medical University from June 2013 to July 2014 were retrospectively analyzed. Results the results of thromboelastogram, hemagglutination and coagulation were compared in 49 healthy pregnant women. Results compared with the control group, the traditional coagulation items in GDM group were compared with those in the control group. The difference of prothrombin time was statistically significant (P 0.05), but there was no significant difference in activated partial thromboplastin time, fibrinogen and platelet count. Conclusion TEG is more sensitive than traditional coagulation function in monitoring the progression of prethrombotic state in patients with GDM, and is more sensitive to guiding early clinical intervention to alleviate or delay complications. Improving the outcome of mother and child has certain significance.
【作者单位】：重庆医科大学第二附属医院妇产科;
【分类号】：R714.256

【相似文献】