舒芬太尼复合罗哌卡因与芬太尼复合罗哌卡因在分娩镇痛临床应用中的比较

发布时间：2018-02-27 15:46

本文关键词： 舒芬太尼复合罗哌卡因芬太尼复合罗哌卡因分娩镇痛并发症　出处：《中国现代医学杂志》2015年10期 　论文类型：期刊论文

【摘要】：目的比较舒芬太尼复合罗哌卡因与芬太尼复合罗哌卡因在分娩镇痛中的效果。方法选择该院2012年1月-2013年1月妇产科ASAΙ~Ⅱ级足月妊娠初产妇80例,随机分为舒芬太尼复合罗哌卡因组(A组,n=40)及芬太尼复合罗哌卡因(B组,n=40)。A组泵注药物为0.5μg/ml的舒芬太尼+0.09%罗哌卡因100ml,B组泵注药物为2.5μg/ml的芬太尼+0.09%罗哌卡因100ml。观察各组麻醉给药诱导前(T0)、给药后10(T1)、30(T2)、60(T3)、120(T4)和180 min(T5)时平均动脉压MAP、心率(HR)及VAS评分的变化,统计其产程、分娩方式及出生后1和5 min新生儿Apgar评分,同时记录其并发症。结果试验前两组产妇的平均动脉压MAP及心率HR差异均无统计学意义(均P0.05)。A、B组VAS评分降低,两组间在给药后10、30、60、120和180 min,差异有统计学意义(P0.05)。两组产妇的产程间差异无统计学意义;A组1例、B组3例使用吸引器辅助分娩,两组无剖宫产者,比较两组产妇并发症发生率,A组心动过缓、呼吸抑制比例均低于B组(P0.01)。结论舒芬太尼复合罗哌卡因和芬太尼复合罗哌卡因在分娩镇痛中的镇痛效果明显,起效快、镇痛强、对母婴无不良影响等优点,可安全用于分娩镇痛。
[Abstract]:Objective to compare the effect of sufentanil combined with ropivacaine and fentanyl combined ropivacaine in labor analgesia. They were randomly divided into sufentanil combined with ropivacaine group (n = 40) and fentanyl combined with ropivacaine group B (n = 40) and sufentanil 0.09% ropivacaine (n = 0.09% 渭 g / ml) with 0.09% 渭 g / ml ropivacaine 100 ml (n = 10) and fentanyl 0.09% ropivacaine (n = 2. 5 渭 g / ml). The changes of mean arterial pressure (map), heart rate (HRR) and VAS score were observed before induction of anesthetic administration in each group, and 10 minutes after administration of T1, 30 T2, 60 T3, 120 T4) and 180 min T5), and the changes of the mean arterial pressure (map), heart rate (HRR) and VAS score were observed in each group. Results there was no significant difference in the mean arterial pressure (MAP) and heart rate (HR) between the two groups before the trial (P 0.05). The difference between the two groups was statistically significant (P 0.05). There was no significant difference in the labor process between the two groups (P < 0.05). There was no significant difference between the two groups (P < 0.05). There was no significant difference in the labor process between the two groups. There was no significant difference between the two groups (P < 0.05). There was no significant difference between the two groups (P < 0.05). There was no significant difference between the two groups. The rate of bradycardia in group A was lower than that in group B (P 0.01). Conclusion Sufentanil combined with ropivacaine and fentanyl combined with ropivacaine has obvious analgesic effect, quick onset and strong analgesia. It has no adverse effects on mother and child, and can be safely used for labor analgesia.
【作者单位】：贵港市妇幼保健院手麻科;贵港市妇幼保健院妇产科;
【分类号】：R714.3

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