更年期综合征临床症状与雌激素水平的关系研究

发布时间：2018-03-01 17:01

本文关键词： 更年期临床症状雌二醇卵泡刺激素　出处：《湖北科技学院学报(医学版)》2016年06期 　论文类型：期刊论文

【摘要】：目的探讨更年期综合征的临床症状与雌激素水平之间的关系。方法选择在我院接受治疗的120例更年期综合征女性患者作为研究对象,根据其更年期综合征症状将其分为轻度组(A组)43例,中度组(B组)38例,重度组(C组)39例。选择同期在我院接受健康体检的育龄阶段健康女性45例作为对照组。测定并比较四组研究对象的雌二醇(E2)和卵泡刺激素(FSH)水平,探讨其与更年期妇女综合征临床症状之间的相关性。结果 A组FSH明显高于对照组(P0.05),E2明显低于对照组(P0.05);B组FSH明显高于A组(P0.05),E2明显低于A组(P0.05);C组FSH明显高于B组(P0.05),E2明显低于B组(P0.05)。更年期综合征临床症状的严重程度与FSH呈正相关(P0.05),与E2呈负相关(P0.05)。结论血清FSH升高,以及E2降低会增加更年期综合征患病的风险以及女性相关更年期临床症状的发生率和严重程度。利用FSH和E2可以对女性更年期临床症状的治疗和改善进行指导和评价。
[Abstract]:Objective to investigate the relationship between clinical symptoms and estrogen level in climacteric syndrome. According to the symptoms of climacteric syndrome, it was divided into mild group (n = 43) and moderate group (n = 38). 39 cases of severe group C were selected as control group. The levels of estradiol estradiol (E2) and follicle stimulating hormone (FSHs) were measured and compared among 45 healthy women in the same period of health examination in our hospital. Results FSH in group A was significantly higher than that in control group (P 0.05) and E2 was significantly lower than that in group B (P 0.05). The level of FSH in group A was significantly higher than that in group A (P 0.05) and FSH in group C was significantly higher than that in group B (P 0.05 E 2). The severity of clinical symptoms of climacteric syndrome was positively correlated with FSH and negatively correlated with E2. Conclusion Serum FSH is increased. The decrease of E2 will increase the risk of menopausal syndrome and the incidence and severity of menopausal symptoms in women. The use of FSH and E2 can be used to guide and evaluate the treatment and improvement of menopausal symptoms.
【作者单位】：东莞市樟木头人民医院第一门诊;
【分类号】：R711.75

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