宫颈癌的生物标志物分析及其临床应用前景

发布时间：2018-03-02 21:26

本文选题：宫颈癌　切入点：生物标志物　出处：《现代预防医学》2015年11期 　论文类型：期刊论文

【摘要】：宫颈癌是一种常见的妇科恶性肿瘤,其发病率位于女性肿瘤第二位,仅次于乳腺癌。目前宫颈癌呈年轻化的趋势,鉴于宫颈癌的早期治愈率很高,早发现早治疗是应对宫颈癌的最有效方式,但目前的宫颈涂片检查敏感度低,重复性差等特点是制约早期诊断的一个重要瓶颈。人乳头瘤病毒的感染是宫颈癌发生的明确病因,因此,寻找人乳头瘤病毒调节的生物标志物对于疾病的早期发现、预防、治疗以及预后都有着十分重要的意义。在此,本文对宫颈癌的一些特异性分子标志物进行了总结,这些标志物的顺利开发在临床检测和治疗上有着非常重要的意义。
[Abstract]:Cervical cancer is a common gynecologic malignant tumor, its incidence rate is the second highest in women, second only to breast cancer. At present, cervical cancer is becoming younger, since the early cure rate of cervical cancer is very high. Early detection and early treatment is the most effective way to deal with cervical cancer. However, the characteristics of low sensitivity and poor reproducibility of cervical smear are an important bottleneck restricting early diagnosis. The infection of human papillomavirus is the clear cause of cervical cancer. Therefore, searching for biomarkers of human papillomavirus regulation plays an important role in the early detection, prevention, treatment and prognosis of cervical cancer. The successful development of these markers is of great significance in clinical detection and treatment.
【作者单位】：衡水市第四人民医院妇产科;
【分类号】：R737.33

【共引文献】