温肾活血中药结合克罗米芬促排卵治疗排卵障碍性不孕症的临床疗效分析及安全性评价

发布时间：2018-03-03 02:35

本文选题：温肾活血中药　切入点：克罗米芬　出处：《中医临床研究》2016年36期 　论文类型：期刊论文

【摘要】：目的:研究温肾活血中药结合克罗米芬促排卵治疗排卵障碍性不孕症的临床疗效及安全性。方法:病例资料来源于我院2014年1月—2016年1月就诊的100例排卵障碍性不孕症患者。随机分组方法:随机数字表法。100例患者分为西医组和中西结合组。西医组采用克罗米芬促排卵治疗;中西结合组采用温肾活血中药结合克罗米芬促排卵治疗。比较1周期排卵率、妊娠率;2先兆流产率、卵巢过度刺激率;3干预前和干预后患者性激素FSH、E2、LH、P的差异。结果:1中西结合组对比西医组周期排卵率、妊娠率更高,P0.05;2中西结合组、西医组先兆流产率相似,P0.05;中西结合组卵巢过度刺激率低于西医组,P0.05;3干预前两组性激素FSH、E2、LH、P相似,P0.05;干预后中西结合组对比西医组性激素E2、P改善更显著,P0.05。而两组的FSH、LH治疗前后差异不显著,P0.05。结论:温肾活血中药结合克罗米芬促排卵治疗排卵障碍性不孕症的临床疗效及安全性高,可有效改善患者临床症状和性激素水平,促进排卵,提高妊娠率,作用安全,无严重不良反应,值得推广。
[Abstract]:Objective: to study the clinical efficacy and safety of warming kidney and activating blood circulation Chinese medicine combined with clomiphene in the treatment of ovulatory infertility. Methods: from January 2014 to January 2016, 100 cases of ovulation disorders were treated in our hospital. Methods: 100 patients were randomly divided into western medicine group and western medicine group. Western medicine group was treated with clomiphene to promote ovulation. The combination group was treated with traditional Chinese medicine of warming kidney and activating blood circulation combined with clomiphene to promote ovulation. The difference of sex hormone FSHE _ 2N LHH _ (P) between the two groups before and after the intervention was analyzed. Results compared with the Western medicine group, the ovulation rate and pregnancy rate of the two groups were higher than those of the Western and Western combination group, and the pregnancy rate was higher than that of the Western and Western combination group, and the pregnancy rate was higher than that of the Western medicine group. The rate of threatened abortion in western medicine group was similar to that in western medicine group (P0.05), and the rate of ovarian hyperstimulation in combination group was lower than that in western group before intervention (P 0.05). After intervention, the improvement of sex hormone E _ 2N _ (P) in the combination group was more significant than that in western group (P _ (0.05)), and the treatment of FSHLH in both groups was more significant than that in western group (P _ (0.05)). Conclusion: the combination of traditional Chinese medicine for warming kidney and activating blood circulation combined with clomiphene to promote ovulation is effective and safe in the treatment of ovulatory infertility. It can effectively improve the clinical symptoms and sex hormone levels, promote ovulation, increase pregnancy rate, effect safety, no serious adverse reactions, it is worth popularizing.
【作者单位】：梅州市第二中医医院;
【分类号】：R711.6

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