6例伴MELF浸润方式的子宫内膜癌患者临床分析

发布时间：2018-03-06 10:02

  本文选题：MELF浸润　切入点：子宫内膜样癌　出处：《复旦学报(医学版)》2015年02期 　论文类型：期刊论文

【摘要】：目的分析MELF(microcystic elongated and fragmented)浸润在子宫内膜癌诊断及预后判断中的临床价值。方法回顾性分析2011年3月至2013年6月复旦大学附属妇产科医院收治的6例子宫内膜癌伴有MELF浸润病理类型患者的病例资料。分析MELF浸润与子宫内膜癌临床病理类型、分期及预后的相关性。结果患者年龄43~67岁,中位年龄56.5岁,临床表现以阴道不规则出血或阴道异常排液为主。1例为子宫内膜样腺癌I级合并透明细胞癌ⅠB期;1例子宫内膜样腺癌Ⅰ级ⅠB期;3例子宫内膜样腺癌Ⅰ级ⅢC期;1例子宫内膜样腺癌Ⅰ级ⅣB期。其中4例存在淋巴结转移,5例存在脉管内转移。术后随访5~29个月,均未见复发及转移。结论 MELF浸润多见于较晚期子宫内膜样腺癌,多伴有淋巴结侵犯。存在MELF浸润的子宫内膜癌应尤其注意是否存在脉管累及及淋巴结转移。
[Abstract]:Objective to analyze the clinical value of MELF(microcystic elongated and fragile infiltration in the diagnosis and prognosis of endometrial carcinoma. Methods six cases of endometrial carcinoma with MELF were retrospectively analyzed from March 2011 to June 2013 in the Department of Obstetrics and Gynecology, Fudan University affiliated Hospital of Obstetrics and Gynecology. Clinical data of patients with infiltrating pathological type. The clinicopathologic types of MELF invasion and endometrial carcinoma were analyzed. Results the age of the patients was 4367 years old and the median age was 56.5 years old. The clinical manifestations were irregular vaginal bleeding or abnormal vaginal effusion in 1 case of endometrial adenocarcinoma grade I with clear cell carcinoma stage 鈪，

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