三维能量成像检测宫颈癌与MVD表达的研究

发布时间：2018-03-11 07:36

本文选题：超声能量多普勒　切入点：血管指数　出处：《中国超声医学杂志》2017年09期 　论文类型：期刊论文

【摘要】：目的 (1)探讨宫颈癌能量多普勒血管指数(VI)及其与病理MVD表达的相关性;(2)宫颈癌经阴道三维超声定量指标(VI)与临床分期相关性。方法选取在本院治疗、资料完整的宫颈癌患者60例,临床诊断慢性宫颈炎患者20例。利用计算机相关软件计算其VI。宫颈癌术后病理经MVD免疫组化检测,结果与三维超声重建分析宫颈癌内部及周边血流分型、血管指数,对宫颈癌浸润和(或)转移情况进行宫颈癌临床分期。结果 (1)三维超声能量多普勒显示率差异具有显著统计学意义(χ~2=30.423,P0.001);(2)VI差异有显著性(t=6.32,P0.001);(3)血管密度差异有显著性(t=11.697,P0.001)。结论 (1)通过经腹部、经阴道三维彩色血管能量成像显示VI与病理MVD高度相关;(2)宫颈癌经阴道三维超声定量指标(VI)与临床分期高度相关。
[Abstract]:Objective (1) to investigate the cervical cancer vascular Doppler energy (VI) index and its correlation with pathological expression of MVD; (2) cervical carcinoma transvaginal three-dimensional ultrasound quantitative index (VI) and the correlation between clinical staging methods. Treatment in the hospital, complete data of patients with cervical cancer in 60 cases, the clinical diagnosis of 20 patients with chronic cervicitis calculate the VI. cases. Cervical cancer operation by using computer software related pathology by MVD immunohistochemistry, and the results of 3D ultrasound reconstruction of blood flow within and around the cervical cancer type, vascular index of cervical cancer invasion and metastasis (or) in clinical staging of cervical carcinoma. Results (1) three dimensional ultrasound energy Doppler the display rate difference was statistically significant (~2=30.423, P0.001); (2) there was significant difference in VI (t=6.32, P0.001); (3) there was significant difference in microvessel density (t=11.697, P0.001). Conclusion (1) by transabdominal and transvaginal three-dimensional color vessel Energy imaging showed that VI was highly correlated with pathological MVD; (2) the transvaginal three-dimensional echocardiographic quantitative index (VI) of cervical cancer was highly correlated with clinical staging.

【作者单位】：海口市人民医院超声医学科;
【基金】：海南省自然科学基金(No.811153)
【分类号】：R445.1;R737.33

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