宫腔镜手术联合孕激素治疗早期子宫内膜癌的临床分析

发布时间：2018-03-13 00:30

本文选题：早期子宫内膜癌　切入点：宫腔镜　出处：《中国妇产科临床杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的探讨早期子宫内膜癌患者宫腔镜手术结合孕激素保留生育功能治疗的临床有效性及可行性。方法回顾性分析西北妇女儿童医院2011年9月至2016年12月接受宫腔镜手术联合孕激素保留生育功能治疗的9例早期子宫内膜癌患者的临床及随访资料。结果 9例患者中,初次治疗完全缓解8例,复发1例,初次治疗结束后中位随访时间37个月(3~58个月),所有患者均存活。其中7例患者共妊娠8次,妊娠成功5例,4例患者足月或近足月活产儿。治疗期间5例患者出现体质量增加,2例出现乳房胀痛,1例肝功轻度异常,1例轻度宫腔粘连,经对症处理后均好转,无严重不良事件发生。结论在严格掌握适应证的前提下,对有强烈生育愿望的年轻早期子宫内膜癌患者行宫腔镜手术联合孕激素方案的保留生育功能治疗是安全、有效、可行的。
[Abstract]:Objective to investigate the clinical efficacy and feasibility of hysteroscopic surgery combined with progesterone fertility retention in early endometrial carcinoma patients. Methods the clinical efficacy and feasibility of hysteroscopic surgery combined with progesterone retention in fertility were retrospectively analyzed from September 2011 to December 2016 in Northwest Women's and Children's Hospital. Clinical and follow-up data of 9 patients with early endometrial carcinoma treated by endoscopic surgery combined with progesterone fertility preserving therapy. There were 8 cases of complete remission and 1 case of recurrence after the first treatment. The median follow-up time was 37 months to 58 months after the first treatment. All the patients survived, among them, 7 cases were pregnant for 8 times. During the period of treatment, 5 cases had increased body mass, 2 cases had breast distention pain, 1 case had mild abnormal liver function and 1 case had mild intrauterine adhesion, all of them were improved after treatment. Conclusion under the condition of strict indication, it is safe and effective to perform hysteroscopic surgery combined with progesterone regimen to treat young early endometrial carcinoma patients with strong desire to reproduce. Feasible.
【作者单位】：西北妇女儿童医院妇二科;郑州大学第三附属医院妇产科;
【基金】：陕西省科学技术研究发展计划项目(2014SF2-06)
【分类号】：R737.33

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