妊娠期糖尿病产妇静脉滴注催产素引产的滴速调控及敏感性对比分析

发布时间：2018-03-14 18:28

本文选题：妊娠期糖尿病　切入点：催产素　出处：《重庆医学》2015年07期 　论文类型：期刊论文

【摘要】：目的探讨静脉滴注催产素对妊娠期糖尿病(GDM)产妇引产过程中滴速的调控方法以及GDM对催产素敏感性的影响。方法选择静脉滴注催产素引产的GDM初产妇196例为GDM组,同期经催产素引产的非GDM初产妇371例为对照组。各组根据不同的输注浓度(5、10mU/mL)及滴速调节方式(等差/等比)分别分为A1、A2、B1、B2组。对比分析各组引产开始至最佳有效宫缩时间、催产素用量、引产成功率、新生儿窒息率以及不良反应发生率。结果 GDM组至最佳宫缩时间A1组最长,B2组最短,A2组显著长于B2组(P0.05);与对照组比较,浓度及滴速相同情况下GDM组至最佳宫缩时间均分别显著长于对照组(P0.05),催产素用量显著高于对照组(P0.05)。结论 GDM会降低产妇对催产素引产的敏感性,催产素以10mU/mL、8滴/min起、等比递增调控是安全有效的调控模式。
[Abstract]:Objective to investigate the effect of intravenous oxytocin on the rate of induced labor in pregnant women with diabetes mellitus (GDM) and the effect of GDM on the sensitivity of oxytocin. Methods 196 cases of GDM primipara who were induced by oxytocin were selected as GDM group. At the same time, 371 cases of non-#en0# primipara induced by oxytocin were divided into two groups according to different infusion concentration (510mU / mL) and droplet velocity regulation (equal difference / equal ratio). The time from induction of labor to optimal effective uterine contraction in each group was compared and analyzed. Results the dosage of oxytocin, the success rate of induced labor, the rate of asphyxia neonatorum and the incidence of adverse reactions were significantly longer in group A _ 2 than in group A _ 2 and group A _ 2 from group A _ 1 to group A _ 2.Compared with the control group, there was no significant difference between group A _ 2 and group B _ 2. Under the same concentration and droplet rate, the optimal uterine contraction time of GDM group was significantly longer than that of control group (P 0.05), and the dosage of oxytocin was significantly higher than that of control group (P 0.05). Conclusion GDM can decrease the sensitivity of parturient to oxytocin induction. Increasing equal ratio regulation is a safe and effective regulation mode.
【作者单位】：海南医学院附属医院产科;
【分类号】：R714.256

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