对氧磷酶-1酶活性在子宫内膜异位症诊断及分期中的价值

发布时间：2018-03-22 23:13

  本文选题：子宫内膜异位症　切入点：PON酶活性　出处：《现代妇产科进展》2017年11期 　论文类型：期刊论文

【摘要】：目的:探讨子宫内膜异位症(EMs)患者外周血对氧磷酶-1(PON1)酶活性作为疾病诊断及其病情严重程度的指标的可能性。方法:选取近16年EMs患者外周血PON1酶活性测定的相关文献进行Meta分析。比较其在EMs和非EMs良性病变育龄期妇女外周血中,以及其在不同EMs分期患者外周血中的差异。结果:EMs患者外周血中PON1酶活性较非EMs良性病变女性显著降低(OR=-51.27,95%CI为-72.52~-30.02,P0.05),Ⅲ~Ⅳ期明显低于Ⅰ~Ⅱ期(OR=-45.31,95%CI为-60.47~-30.20,P0.05)。结论:PON1活性与EMs发生、发展密切相关,测定患者血PON1酶活性可作为EMs诊断、分期的血清学指标。
[Abstract]:Objective: to investigate the possibility of the activity of paraoxonase-1 (PON1) enzyme in peripheral blood of patients with endometriosis as an indicator of disease diagnosis and severity. Methods: the phase of peripheral blood PON1 enzyme activity in patients with EMs in recent 16 years was selected. Meta analysis was carried out in the relevant literature. The peripheral blood samples of women with benign EMs and non-#en2# diseases were compared with those in the peripheral blood of women of childbearing age. Results the activity of PON1 enzyme in the peripheral blood of the patients with different EMs stages was significantly lower than that of the women with non-benign EMs lesions. Results the activity of PON1 enzyme in the patients with different stages of EMs was significantly lower than that in women with benign EMs lesions. The CI was -72.52% -30.02% -30.02 P 0.05, and that in stage 鈪，

本文编号：1650819