多西环素联合盆腔炎2号方治疗支原体感染盆腔炎疗效及安全性分析

发布时间：2018-03-24 06:26

本文选题：盆腔炎　切入点：支原体感染　出处：《中华中医药学刊》2017年08期

【摘要】：目的:探讨多西环素联合盆腔炎2号方治疗支原体感染盆腔炎疗效及安全性分析。方法:选择2015年1月—2016年6月期间于医院就诊收治的支原体感染盆腔炎患者80例为研究对象,根据随机数字表法将两组患者均分为观察组与对照组各40例,其中对照组患者单独给予多西环素治疗,观察组患者在对照组的基础上联合应用盆腔炎2号方治疗,常规治疗后比较两组患者的临床治疗效果、治疗期间的不良反应情况以及患者子宫血流动力学指标指标之间的差异情况。结果:两组患者治疗后,其中观察组患者的临床治愈患者例数27例、治愈率67.5%,明显的高于对照组患者的19例、47.5%,两组比较差异有统计学意义(P0.05),可以比较;观察组患者的临床治疗无效例数1例、无效率2.5%,明显的低于对照组患者的6例、15.0%,两组比较差异有统计学意义(P0.05),可以比较;观察组患者治疗期间头晕头痛患者2例、恶心呕吐2例、腹泻0例、肝功能异常1例,明显的低于对照组患者的头晕头痛患者5例、恶心呕吐4例、腹泻5例、肝功能异常3例,两组比较差异有统计学意义(P0.05),可以比较;观察组患者的阻力指数(RI)0.86±0.03、搏动指数(PI)2.49±0.09以及平均血流速度(Vmin)0.60±0.03,明显的高于对照组患者的阻力指数(RI)0.80±0.02、搏动指数(PI)2.20±0.06以及平均血流速度(Vmin)0.41±0.02,两组比较差异有统计学意义(P0.05),可以比较。结论:多西环素联合盆腔炎2号方在支原体感染盆腔炎的临床治疗过程中,具有较好的临床治疗效果以及安全性,治疗期间的药物不良反应情况发生率低,可以有效地改善患者的血流动力学指标,在临床上具有极高应用价值,值得进一步推广使用。
[Abstract]:Objective: to investigate the efficacy and safety of doxycycline combined with pelvic inflammatory prescription No. 2 in the treatment of mycoplasma infection with pelvic inflammatory disease. Methods: 80 patients with mycoplasma infection were selected from January 2015 to June 2016. According to the method of random number table, the two groups were divided into observation group (n = 40) and control group (n = 40). The patients in the control group were treated with doxycycline alone, and the patients in the observation group were treated with pelvic inflammatory prescription No. 2 on the basis of the control group. After routine treatment, the clinical efficacy, adverse reactions during treatment and the difference of uterine hemodynamic indexes were compared between the two groups. There were 27 cases of clinical cure in the observation group, and the cure rate was 67.5%, which was significantly higher than that in the control group (19 cases, 47.5%). The difference between the two groups was statistically significant (P 0.05). The effective rate was 2.5, which was significantly lower than that in the control group (6 cases, 15.0%), and the difference between the two groups was statistically significant (P 0.05), and there were 2 cases of dizziness and headache, 2 cases of nausea and vomiting, 0 cases of diarrhea and 1 case of abnormal liver function in the observation group. There were 5 cases of dizziness and headache, 4 cases of nausea and vomiting, 5 cases of diarrhea and 3 cases of abnormal liver function. The difference between the two groups was statistically significant (P 0.05). The resistance index (RI), pulsatile index (Pi) and mean blood flow velocity (Vmin) of the patients in the observation group were 0.86 卤0.03, 2.49 卤0.09 and 0.60 卤0.03, respectively, which were significantly higher than those in the control group (0.80 卤0.02), PII (2.20 卤0.06) and Vmin (0.41 卤0.02). The difference between the two groups was statistically significant. Conclusion: doxycycline combined with pelvic inflammatory recipe No. 2 in the clinical treatment of mycoplasma infection of pelvic inflammatory disease, It has good clinical effect and safety, low incidence of adverse drug reactions during the treatment, can effectively improve the hemodynamic index of patients, has a very high clinical application value, worthy of further promotion and use.
【作者单位】：海南医学院第二附属医院妇产科;
【基金】：海南省卫计委项目(1421320.31A2004)
【分类号】：R711.33

【相似文献】