不同胚胎冷冻保存时间和方法对FET周期临床结局的影响

发布时间：2018-03-24 13:12

  本文选题：玻璃化冷冻　切入点：程序化冷冻　出处：《实用医学杂志》2017年10期

【摘要】：目的:比较分析玻璃化和程序化冷冻卵裂期和囊胚期胚胎保存后复苏效果及临床结局。方法:根据不同冷冻保存时间将胚胎冻融周期分为4组,分别为1~6个月组、7~12个月组、13~24个月组和≥25个月组,比较四组的复苏率、临床妊娠率和流产率。根据不同冷冻保存方法分为玻璃化冷冻组和程序化冷冻组。结果:4组胚胎复苏存活率(98.1%、99.0%、96.8%和95.7%)、临床妊娠率(54.4%、55.4%、49.6%和51.5%)和流产率(10.7%、8.9%、9.45和11.15)相比较,差异均无统计学意义(P0.05)。玻璃化冷冻组胚胎复苏率和临床妊娠率均显著高于程序化冷冻组(P0.05)。结论:胚胎冷冻保存时间不影响解冻后胚胎质量。玻璃化冷冻胚胎方法复苏效果优于程序化冷冻法。囊胚期冻融胚胎可获得较高的临床妊娠率。
[Abstract]:Objective: to compare and analyze the effect and clinical outcome of embryo resuscitation after cryopreservation of vitrification and programmed cryopreservation. Methods: the embryos were divided into 4 groups according to the freezing and thawing periods. The resuscitation rates of the four groups were compared, which were 1 ~ 6 months group, 7 ~ 12 months group, 13 ~ 24 months group and 鈮，

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