腹腔镜手术治疗盆腔炎性包块对T细胞免疫功能及术后恢复的影响

发布时间：2018-03-28 08:27

本文选题：腹腔镜手术　切入点：T细胞　出处：《北华大学学报(自然科学版)》2016年02期

【摘要】：目的探讨腹腔镜手术治疗盆腔炎性包块对T细胞免疫功能及术后恢复的影响.方法随机选取80例盆腔炎患者作为研究对象.随机分为研究组和对照组,研究组采用腹腔镜手术,对照组采用开腹手术,比较两组术后恢复以及对T细胞免疫功能的影响.结果研究组T淋巴细胞亚群手术前后比较差异无统计学意义;开腹组术后CD3+,CD4+,CD8+与术前比较明显降低,72 h时回升,但仍低于术前水平;两组比较,对照组患者的CD3+,CD4+,CD8+降低明显(P0.05);研究组患者术后恢复快,各项指标比较差异具有统计学意义(P0.05).结论盆腔炎性包块患者在开腹手术后会出现细胞免疫功能紊乱,腹腔镜手术对T细胞亚群影响较小,对机体的免疫功能影响小,利于术后恢复.
[Abstract]:Objective to investigate the effect of laparoscopic surgery on T cell immune function and postoperative recovery in patients with pelvic inflammatory mass. Methods 80 patients with pelvic inflammatory disease were randomly divided into study group and control group. The patients in the control group were treated with open surgery to compare the effect of postoperative recovery and T cell immune function. Results there was no significant difference before and after the operation of T lymphocyte subsets in the study group. In the open group, the CD3 CD 4 and CD 8 were significantly decreased at 72 h after operation, but still lower than the preoperative level, the CD3 CD 4 and CD 8 8 in the control group were significantly lower than those in the control group (P 0.05), the recovery of the patients in the study group was faster than that in the control group. Conclusion the patients with pelvic inflammatory mass may have the disorder of cellular immune function after laparotomy, the effect of laparoscopic surgery on T cell subsets is relatively small, and the effect on the immune function of the body is small. It is good for postoperative recovery.
【作者单位】：北华大学附属医院;
【基金】：吉林省科技发展计划项目(2012079)
【分类号】：R713

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