坤泰胶囊与激素治疗围绝经期综合征的循证药物经济学研究

发布时间：2018-03-30 02:03

  本文选题：围绝经期综合征　切入点：激素疗法　出处：《上海中医药杂志》2016年04期

【摘要】：目的评价坤泰胶囊与激素疗法(MHT)治疗围绝经期综合征的经济学基础。方法查找2000~2015年发表的有关坤泰胶囊和MHT治疗围绝经期综合征的随机对照试验(RCT)文献。按照Cochrane系统评价方法进行筛选,采用Revman 5.3软件进行Meta分析,研究两药的临床有效率、安全性和成本情况。结果 1坤泰胶囊治疗围绝经期综合征临床有效率高于激素(P0.05);2坤泰胶囊治疗围绝经期综合征安全性优于激素(P0.05);3临床有效率每升高1个百分点坤泰胶囊所需费用15.2元,激素所需费用12.5元。结论较激素而言,坤泰胶囊治疗围绝经期综合征有效率高、安全性好,临床可酌情运用。
[Abstract]:Objective to evaluate the economic basis of Kuntai capsule and hormone therapy (MHT) in the treatment of perimenopausal syndrome.Methods A randomized controlled trial of Kuntai capsule and MHT in the treatment of perimenopausal syndrome was published from 2000 to 2015.The clinical effective rate, safety and cost of the two drugs were studied by Revman 5.3 software and Meta analysis according to the Cochrane system evaluation method.Results 1 the clinical effective rate of Kun Tai capsule in the treatment of peri-menopausal syndrome was higher than that in the treatment of peri-menopausal syndrome by steroid P0.05TX 2 Kun Tai capsule, which was better than that in the treatment of peri-menopausal syndrome by Kundai capsule, which cost 15.2 yuan for each increase of 1 percentage point of Kuntai capsule.The cost of hormone is 12. 5 yuan.Conclusion compared with hormone, Kun Tai capsule is effective and safe in the treatment of perimenopausal syndrome.
【作者单位】： 贵阳新天药业股份有限公司;上海海天医药科技开发有限公司;
【分类号】：R711.75;R-03
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本文编号：1683843