小剂量右美托咪定对宫颈癌微创术后胃肠道反应的影响

发布时间：2018-03-30 05:22

  本文选题：右美托咪定　切入点：宫颈癌　出处：《中国内镜杂志》2017年07期

【摘要】：目的探讨小剂量右美托咪定对宫颈癌微创术后胃肠道反应的影响。方法选取2014年2月-2016年9月在该院接受宫颈癌微创术的患者94例,依据随机数表法分为观察组(小剂量右美托咪定)和对照组(生理盐水),比较两组患者的恶心、呕吐发生率及胃动素水平。结果观察组47例,Ⅱ级恶心7例,Ⅲ级恶心2例,总发生率为19.15%;对照组47例,Ⅱ级恶心11例,Ⅲ级恶心4例,Ⅳ级恶心2例,总发生率为36.17%,差异具有统计学意义(P0.05)。观察组47例,Ⅱ级呕吐6例,Ⅲ级呕吐1例,总发生率为14.89%;对照组47例,Ⅱ级呕吐4例,Ⅲ级呕吐5例,Ⅳ级呕吐1例,总发生率为21.28%,差异具有统计学意义(P0.05)。术前1 h两组患者的胃动素差异无统计学意义(P0.05)。术后6、12和24 h,观察组患者的胃动素水平明显低于对照组,差异具有统计学意义(P0.05)。结论小剂量右美托咪定能够有效预防和缓解宫颈癌微创术后胃肠道反应,避免胃动素过度释放,值得临床推广。
[Abstract]:Objective to investigate the effect of low dose dexmetomidine on gastrointestinal response after minimally invasive surgery for cervical cancer.Methods from February 2014 to September 2016, 94 patients with cervical cancer received minimally invasive cervical cancer surgery in our hospital. According to the random number table method, 94 patients were divided into two groups: observation group (low dose dexmetomidine) and control group (normal saline). The nausea of the two groups was compared.Incidence of vomiting and motilin level.Results there were 47 cases in observation group, 7 cases in grade 鈪，

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