早期子宫内膜腺癌年轻女性保留生育功能的研究进展

发布时间：2018-03-31 17:34

本文选题：子宫内膜腺癌　切入点：保留生育功能　出处：《河北医科大学》2017年硕士论文

【摘要】：近年来年轻女性子宫内膜癌发病率呈明显上升趋势。年轻女性子宫内膜癌多属于雌激素依赖型,其发生可能是在无孕激素拮抗下的雌激素长期作用下,发生子宫内膜增生症(单纯型或复杂型,伴或不伴不典型增生),甚至癌变,均为子宫内膜腺癌,肿瘤分化好,雌孕激素受体阳性率高,且子宫内膜癌诊断时70%以上的患者属于I期,5年生存率90%,甚至100%,无复发生存率95.0%[1],故此为年轻早期子宫内膜腺癌患者保留生育功能创造了机会。目前主要治疗手段包括药物治疗、手术治疗、手术联合药物治疗等。但多种治疗手段尚未达成统一标准,而且仍存在很大风险。本文旨在对目前早期子宫内膜腺癌年轻女性保留生育功能的相关治疗问题进行总结。
[Abstract]:In recent years, the incidence of endometrial carcinoma in young women has increased significantly.Endometrial carcinoma in young women is mostly estrogen-dependent. It may occur endometrial hyperplasia (simple type or complex type, with or without atypical hyperplasia, or even carcinogenesis) under the long-term action of estrogen without progesterone antagonism.All of them were endometrial adenocarcinoma, the tumor was well differentiated, and the positive rate of estrogen and progesterone receptor was high.More than 70% of the patients with endometrial carcinoma belong to stage I, the 5-year survival rate is 90%, or even 100%, and the recurrence free survival rate is 95.0% [1], thus creating an opportunity for young patients with early endometrial adenocarcinoma to retain their reproductive function.At present, the main treatment methods include drug therapy, surgical treatment, surgery combined with drug therapy.However, a variety of treatments have not yet reached a unified standard, and there are still great risks.This article aims to summarize the current treatment of early endometrial adenocarcinoma in young women with fertility retention.
【学位授予单位】：河北医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.33

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