不同时间宫内放置左炔诺孕酮宫内缓释系统对子宫腺肌病患者的疗效分析

发布时间：2018-04-01 14:05

本文选题：左炔诺孕酮宫内缓释系统　切入点：子宫腺肌病　出处：《第三军医大学学报》2015年19期

【摘要】：目的探讨放置左炔诺孕酮宫内缓释系统(曼月乐)治疗子宫腺肌病的最佳时机,寻求在达到满意治疗效果的同时,降低治疗副作用的有效方法。方法回顾性分析2002-2014年本院使用曼月乐治疗子宫腺肌病1 372例,按照放置时间分成3组:月经干净后3~7 d(A组)、月经第3~5天(B组)和清宫术后立即放置(C组)。评价放置曼月乐后的疼痛缓解、月经量改变、阴道点滴出血和闭经情况。结果 3组患者放置曼月乐后,疼痛缓解效果和闭经发生率差异无统计学意义(P0.05);C组比A、B组的月经量减少趋势更明显(P0.05);3组月经间期阴道点滴出血发生率差异有统计学意义(P0.05),A、B组的阴道点滴出血的时间更长(P0.05)。结论月经周期不同时段放置曼月乐均可明显缓解子宫腺肌病引起的痛经,清宫术后放置曼月乐后的激素相关副反应更少,可获取最佳治疗效果。
[Abstract]:Objective to explore the best time for the treatment of adenomyosis with levonorgestrel intrauterine sustained-release system (Manyue), and to find out a satisfactory therapeutic effect at the same time. Methods 1 372 cases of adenomyosis were treated with manyue in our hospital from 2002 to 2014. They were divided into three groups according to the time of placing: group A (3 days after menstruation), group B (group B on the 3rd day of menstruation) and group C (group C immediately after operation). The pain relief and menstrual volume were evaluated after the placement of Manyuelo. Results the patients in the three groups were treated with Manyue. There was no significant difference between the effect of pain relief and the incidence of amenorrhea. The decrease trend of menstrual volume in group C was more obvious than that in group A (P 0.05). There was a significant difference in the incidence of vaginal drip bleeding in group A (P 0.05) and group A (P 0.05). Conclusion manyue can relieve dysmenorrhea caused by adenomyosis in different periods of menstrual cycle. The hormone-related side effects after placement of manyue were less, and the best therapeutic effect could be obtained.
【作者单位】：第三军医大学西南医院妇产科;
【分类号】：R711.71

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